78440-45-6Relevant articles and documents
A novel asymmetric synthesis of 2-azetidinones from achiral precursors
Zhou, Feng,Detty, Michael R.,Lachicotte, Rene J.
, p. 585 - 588 (1999)
Asymmetric synthesis of (3S,4S)-3-phenylsulfonyl-4-phenylazetidin-2- ones in up to 46% ee from achiral amines and 2-phenylsulfonyl-3- phenylpropenoyl chloride was achieved with chiral Lewis-acid catalysis by salen-copper(II) complexes derived from (1R,2R)
Synthesis and antimicrobial screening of some 3-(phenylsulfonyl)- 2H-chromen-2-ones
Edayadulla,Babu,Ramesh
, p. 1 - 4 (2013/12/04)
In this study, we have investigated the synthetic routes for the preparation of 3-sulfonyl coumarin 3 starting from phenylsulfonyl acetate 2 in the presence of mild base pyridine and piperidine and simple peroxide oxidation of sulphide 6 to sulfones 7 and their antimicrobial activities.
Knoevenagel reaction in [MMIm][MSO4]: Synthesis of coumarins
Verdia, Pedro,Santamarta, Francisco,Tojo, Emilia
experimental part, p. 4379 - 4388 (2011/08/06)
The ionic liquid 1,3-dimethylimidazolium methyl sulfate, [MMIm][MSO 4], together with a small amount of water (the amount taken up by the ionic liquid upon exposure to air), acts efficiently as both solvent and catalyst of the Knoevenagel condensation reactions of malononitrile with 4-substituted benzaldehydes, without the need for any other solvent or promoter, affording yields of 92%-99% within 2-7 min at room temperature. When L-proline is used as an additional promoter to obtain coumarins from o- hydroxybenzaldehydes, the reaction also proceeds in high yields. Work-up is very simple and the ionic liquid can be reused several times. Some of the coumarins obtained are described for the first time.
