78443-73-9

Basic information

• Product Name: 2-(benzyloxy)-4,6-dichlorobenzaldehyde
• Synonyms: 2-(benzyloxy)-4,6-dichlorobenzaldehyde
• CAS NO: 78443-73-9
• Molecular Weight: 281.138
• Mol File: 78443-73-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(benzyloxy)-4,6-dichlorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzyloxy)-4,6-dichlorobenzaldehyde(78443-73-9)
• EPA Substance Registry System: 2-(benzyloxy)-4,6-dichlorobenzaldehyde(78443-73-9)

Safety Data

• Hazardous Substances Data: 78443-73-9(Hazardous Substances Data)

Usage

General Description

2-(benzyloxy)-4,6-dichlorobenzaldehyde is a chemical compound with the molecular formula C15H11Cl2O2. It is a derivative of benzaldehyde with two chlorine atoms and a benzyloxy group attached to the benzene ring. 2-(benzyloxy)-4,6-dichlorobenzaldehyde is commonly used in organic synthesis and pharmaceutical research as an intermediate for the synthesis of various organic compounds. It has been studied for its potential biological and pharmacological activities, and it is important for its role in the development of new drugs and biologically active molecules. The compound's unique structure and properties make it valuable for a range of applications in the fields of chemistry and medicine.

Upstream product

• 100-39-0 benzyl bromide 
• 78443-72-8 4,6-dichlorosalicylaldehyde 

Downstream Products

• 1461-25-2 tetra-n-butyltin(IV) 
• 78443-74-0 (E)-3-<2,4-dichloro-6-(phenylmethoxy)phenyl>-2-propenal 
• 78444-23-2 (+)-trans-(E)-6-<2-<2,4-dichloro-6-(phenylmethoxy)phenyl>ethyl>-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one 
• 78443-80-8 (E)-6-<2-<2,4-dichloro-6-(phenylmethoxy)phenyl>ethenyl>-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one 
• 78443-80-8 (E)-6-<2-<2,4-dichloro-6-(phenylmethoxy)phenyl>ethenyl>-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one 
• 78443-78-4 methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate 
• 78443-77-3 methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-5-hydroxy-3-oxo-6-heptenoate 
• 78443-79-5 (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoic acid 

Relevant articles and documents

Choline Hydroxide as a Versatile Medium for Catalyst-Free O-Functionalization of Phenols

A versatile synthetic protocol for benzyl phenyl ether preparation via O-alkylation of phenolic oxygen with readily available benzyl derivatives was demonstrated. The newly designed procedure was carried out using an eco-friendly medium, room-temperature ionic liquid (choline hydroxide), under metal- and base-catalyst-free aerobic conditions. The reaction platform was also successfully applied to phenol protection strategy.

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 2. Structural modification of 7-(substituted aryl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives

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SUBSTITUTED PYRANONE INHIBITORS OF CHOLESTEROL SYNTHESIS

6-Phenyl-, phenylalkyl-and phenylethenyl-4-hydroxytetrahydropyran-2-ones in the 4(R)-trans stereoisomeric forms are potent inhibitors of cholesterol synthesis by virtue of their ability to inhibit the enzyme, 3-hydroxy-3-methylglutaryl-coenzyme A reductas