785-78-4

Basic information

• Product Name: 4-ACETYLBIBENZYL
• Synonyms: 1-[4-(2-Phenylethyl)phenyl]ethanone;4-ACETYLBIBENZYL;1-[4-(2-phenylethyl)phenyl]ethan-1-one;1-(4-Acetylphenyl)-2-phenylethane;4'-Phenethylacetophenone;4-ACETYLBIBENZYL(WXG02447)
• CAS NO: 785-78-4
• Molecular Formula: C₁₆H₁₆O
• Molecular Weight: 224.3
• EINECS: 212-323-6
• Mol File: 785-78-4.mol
• Article Data: 32

Chemical Properties

• Melting Point: 68 °C
• Boiling Point: 342.7 °C at 760 mmHg
• Flash Point: 146.2 °C
• Appearance: /
• Density: 1.045 g/cm³
• Vapor Pressure: 7.4E-05mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 4-ACETYLBIBENZYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETYLBIBENZYL(785-78-4)
• EPA Substance Registry System: 4-ACETYLBIBENZYL(785-78-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 785-78-4(Hazardous Substances Data)

Usage

Uses

4-Acetylbibenzyl is a useful research intermediate for organic synthesis.

InChI:InChI=1/C16H16O/c1-13(17)16-11-9-15(10-12-16)8-7-14-5-3-2-4-6-14/h2-6,9-12H,7-8H2,1H3

Upstream product

• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 75-36-5 acetyl chloride 
• 7439-15-8 1-(4-ethylphenyl)-2-phenylethane 
• 83168-79-0 1-phenyl-2-(trifluorosilyl)ethane 
• 109613-00-5 4-acetophenyl triflate 
• 99-90-1 para-bromoacetophenone 
• 1657-55-2 1,2-bis(4-methoxyphenyl)ethane 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 
• 13329-40-3 4-Iodoacetophenone 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 34420-17-2 (2-phenylethyl)boronic acid 
• 940-41-0 1-phenyl-2-(trichlorosilyl)ethane 

Downstream Products

• 38110-26-8 (E)-3-(4-Phenethyl-phenyl)-but-2-enoic acid methyl ester 
• 73932-75-9 4'-(β-phenylethyl)-3-(dimethylamino)propiophenone 
• 10509-24-7 1-ethynyl-4-(2-phenylethyl)benzene 
• 24585-99-7 p-(2-Phenylethyl)-phenyl-glyoxal 
• 94029-37-5 1-Phenyl-2-(4-dibromacetyl-phenyl)-ethan 
• 215368-65-3 1-[4-(2-indolyl)phenyl]-2-phenylethane 
• 838862-58-1 1-[4-(1-benzyl-2-indolyl)phenyl]-2-phenylethane 
• 10509-25-8 C₃₂H₂₆ 
• 55005-29-3 α-methyl-p-phenethylbenzylamine hydrochloride 
• 1228271-10-0 4-[5-(4-Phenethyl-phenyl)-isoxazol-3-yl]-benzoic acid 
• 1353585-92-8 2-(1H-imidazol-1-yl)-1-[4-(2-phenylethyl)phenyl]ethanone hydrochloride 
• 28179-32-0 2-bromo-1-[4-(2-phenylethyl)phenyl]ethanone 
• 1381870-28-5 5-phenyl-2-[4-(2-phenylethyl)phenyl]indole 

Relevant articles and documents

Nickel-Catalyzed Regiodivergent Reductive Hydroarylation of Styrenes

We report a ligand-controlled nickel-catalyzed reductive hydroarylation of styrenes with predictable and controllable regioselectivity. With a diamine ligand, the reaction produces selective linear hydroarylation products. Alternatively, with a chiral PyrOx ligand, branch-selective enantioenriched 1,1-diarylalkane products are obtained. Preliminary mechanistic results are consistent with a reductive Heck process.

Generation of Alkyl Radical through Direct Excitation of Boracene-Based Alkylborate

The generation of tertiary, secondary, and primary alkyl radicals has been achieved by the direct visible-light excitation of a boracene-based alkylborate. This system is based on the photophysical properties of the organoboron molecule. The protocol is applicable to decyanoalkylation, Giese addition, and nickel-catalyzed carbon-carbon bond formations such as alkyl-aryl cross-coupling or vicinal alkylarylation of alkenes, enabling the introduction of various C(sp3) fragments to organic molecules.

Preparation of Alkyl Indium Reagents by Iodine-Catalyzed Direct Indium Insertion and Their Applications in Cross-Coupling Reactions

An efficient method for the synthesis of alkyl indium reagent by means of an iodine-catalyzed direct indium insertion into alkyl iodide in THF is reported. The thus-generated alkyl indium reagents effectively underwent Pd-catalyzed cross-coupling reactions with various aryl halides, exhibiting good compatibility to a variety of sensitive functional groups. By replacing THF with DMA and using 0.75 equiv of iodine, less reactive alkyl bromide could be used as substrate for indium insertion with equal ease.