78574-94-4Relevant articles and documents
The use of two-phase acid hydrolysis method of preparing ring [...] (by machine translation)
-
Paragraph 0024-0066, (2019/07/08)
The invention belongs to the field of pharmaceutical chemicals, in particular to the use of double-phase acid hydrolysis method of preparing ring [...], including astragaloside as raw materials, and the organic phase and the acid solution of the two-phase acid aqueous solution mixing, reaction, after-treatment, to obtain the ring [...]; wherein organic phase immiscible with water or slightly soluble, ring [...] in the organic phase is greater than the solubility of the aqueous phase. This invention utilizes the double-phase acid hydrolysis method for preparing ring [...], making acid is hydrolyzed to generate ring [...] distribution in the organic phase, thereby avoiding the ring [...] in violent acid aqueous phase into the shortcoming of the [...], effectively protect the stability of the ring [...], [...] greatly improves the yield of the ring, and the step is simple, low cost, and is suitable for industrial production; through the standstill, layered, extraction, silica gel column chromatography separation to obtain high-purity [...]. (by machine translation)
Triterpene glycosides from astragalus. Structure of cyclolehmanoside C from A. lehmannianus
Zhanibekov,Naubeev,Uteniyazov,Bobakulov, Kh. M.,Abdullaev
, p. 475 - 477 (2013/09/02)
The structure of a new cycloartane triterpene glycoside, cyclolehmanoside C, that was isolated from the aerial part of Astragalus lehmannianus Bunge (Leguminosae) was established as 20R,24S-epoxycycloartane-3β,6α, 16β,24-tetraol 3-O-[β-D-glucopyranosyl(1→2)]- β-D-glucopyranoside-25-O-β-D-glucopyranoside.
Compositions and Methods for Increasing Telomerase Activity
-
Page/Page column 14, (2010/12/18)
The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and for enhancing proliferation of stem and progenitor cells.