78589-15-8 Usage
Description
1-(4-dimethylamino-2-methoxyphenyl)ethanone, also known as DMAP, is a chemical compound with the molecular formula C11H15NO2. It is a ketone that is commonly used as a reagent and catalyst in organic synthesis. DMAP is known for its ability to catalyze the acylation of alcohols and amines, making it a valuable tool in the production of pharmaceuticals and agrochemicals. This pale yellow solid has a melting point of 66-68 °C and a characteristic amine odor. It is considered to be a stable compound with low reactivity, which contributes to its utility in organic chemistry research.
Uses
Used in Pharmaceutical Industry:
1-(4-dimethylamino-2-methoxyphenyl)ethanone is used as a catalyst for the acylation of alcohols and amines, which is a crucial step in the synthesis of various pharmaceutical compounds. Its ability to facilitate these reactions makes it an essential component in the development of new drugs and medicines.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(4-dimethylamino-2-methoxyphenyl)ethanone is used as a catalyst in the production of various agrochemicals, including pesticides and herbicides. Its role in catalyzing key reactions allows for the efficient synthesis of these compounds, which are vital for agricultural productivity and pest control.
Used in Organic Chemistry Research:
DMAP is also used as a reagent and catalyst in organic chemistry research. Its stability and low reactivity make it an ideal candidate for exploring new reaction pathways and developing innovative synthetic methods. This contributes to the advancement of knowledge in the field of organic chemistry and the discovery of new chemical compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 78589-15-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,5,8 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 78589-15:
(7*7)+(6*8)+(5*5)+(4*8)+(3*9)+(2*1)+(1*5)=188
188 % 10 = 8
So 78589-15-8 is a valid CAS Registry Number.
78589-15-8Relevant articles and documents
Synthesis and identification of new flavonoids targeting liver X receptor β involved pathway as potential facilitators of Aβ clearance with reduced lipid accumulation
Hu, Yun,Yang, Yaqi,Yu, Yanjun,Wen, Gesi,Shang, Nana,Zhuang, Wei,Lu, Dihan,Zhou, Binhua,Liang, Baoxia,Yue, Xin,Li, Feng,Du, Jun,Bu, Xianzhang
, p. 6033 - 6053 (2013/09/02)
Alzheimer's disease (AD) is associated with impaired Aβ degradation in the brain. Enhancing the process of Aβ clearance is an attractive potential AD therapy. Treatment with LXR agonists may reduce Aβ levels in vivo. However, the clinical potential of man
Infrared study of polysubstitution effects in benzophenones and acetophenones: contribution of inter and intracycle interaction mechanisms
Goethals, G.,Nadio, L.,Uzan, R.
, p. 199 - 204 (2007/10/02)
The carbonyl stretching frequencies of substituted 2-Me, 2,6-diMe, 2-MeO benzophenones and 2-Me, 2-MeO acetophenones have been measured in diluted CCl4 solutions.Two interaction mechanisms are observed.In X, Y substituted benzophenones with X on the same cycle as the ortho group and Y on the other cycle, it is shown that for X=Y, the effect of Y is greater than that of X except for very strong electron-releasing substituents.In this last case, the observed enhancement is attributed to the joint effects of intercycle interactions excercised on X and Y and of intracycle interaction on X.These results are corroborated by the study of substituted acetophenones in which only the intracycle mechanism can play a role.
