78602-03-6

Basic information

• Product Name: 3-((1H-indol-3-yl)(phenyl)methyl)-1-methyl-2-phenyl-1H-indole
• Synonyms: 3-((1H-indol-3-yl)(phenyl)methyl)-1-methyl-2-phenyl-1H-indole
• CAS NO: 78602-03-6
• Molecular Weight: 412.534
• Mol File: 78602-03-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-((1H-indol-3-yl)(phenyl)methyl)-1-methyl-2-phenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((1H-indol-3-yl)(phenyl)methyl)-1-methyl-2-phenyl-1H-indole(78602-03-6)
• EPA Substance Registry System: 3-((1H-indol-3-yl)(phenyl)methyl)-1-methyl-2-phenyl-1H-indole(78602-03-6)

Safety Data

• Hazardous Substances Data: 78602-03-6(Hazardous Substances Data)

Upstream product

• 51626-58-5 (1H-indol-3-yl)(phenyl)methanol 
• 3558-24-5 1-methyl-2-phenyl-1H-indole 
• 120-72-9 indole 
• 67335-20-0 3,3'-(phenylmethylene)bis(1-methyl-2-phenyl-1H-indole) 

Relevant articles and documents

FeCl3·6H2O as a Mild Catalyst for Nucleophilic Substitution of Symmetrical Bis(indoyl)methanes

In this paper, unsymmetrical bis(indolyl)methane (BIM) and 3-alkylindole derivatives are smoothly synthesized from symmetrical BIMs with a variety of nucleophiles including heteroaromatic/aromatic compounds, allylsilane and alkynylsilane. FeCl3·6H2O is found to be a mild and highly effective catalyst for this nucleophilic substitution reaction in which N-methyl-2-phenylindole behaves as a good leaving group in the Csp3-Csp2 bond cleavage reaction. The operational ease, nonexpensive and environmentally friendly catalyst, mild reaction conditions, broad functional group tolerance, and scalability of this reaction strategy are advantages of the present procedure.

Fluorinated Alcohol-Mediated SN1-Type Reaction of Indolyl Alcohols with Diverse Nucleophiles

This paper describes an efficient SN1-type reaction of 3-indolylmethanols with miscellaneous nucleophiles, featuring a catalyst-free procedure, low cost, wide substrate scope and mild reaction conditions. This approach provides green and efficient methods for the synthesis of diverse 3-substituted indolyl derivatives as well as unsymmetrical bisindolylmethanes and triarylmethanes.