78635-92-4

Basic information

• Product Name: Dimethyl-phosphoramidous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester
• Synonyms: Dimethyl-phosphoramidous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester
• CAS NO: 78635-92-4
• Molecular Weight: 738.777
• Mol File: 78635-92-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Dimethyl-phosphoramidous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyl-phosphoramidous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester(78635-92-4)
• EPA Substance Registry System: Dimethyl-phosphoramidous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester(78635-92-4)

Safety Data

• Hazardous Substances Data: 78635-92-4(Hazardous Substances Data)

Upstream product

• 70063-12-6 Chloro-(N,N-dimethylamino)-methoxyphosphine 
• 67219-55-0 4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine 

Downstream Products

• 78636-00-7 C₅₃H₅₆N₅O₁₅P 

Relevant articles and documents

Automatic synthesis of oligodeoxynucleotides and mixed oligodeoxynucleotides using the phosphoamidite method.

A simplified procedure for making and using the deoxynucleoside phosphoamidites (1 a-d) in the automated synthesis of oligodeoxynucleotides has been developed. The reagents prepared show good stability in solution. The reactivity of the reagents was found

DEOXYNUCLEOSIDE PHOSPHORAMIDITES-A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS

The development of a new class of nucleoside phosphites is described.These compounds are stable to normal laboratory conditions, are activated by mild acid treatment, and are observed to react essentially quantitatively with protected nucleosides.