78637-85-1

Basic information

• Product Name: 3,4-Diaminothiophene dihydrobromide
• Synonyms: 3,4-Diaminothiophene2HCl;3,4-Diaminothiophene dihydrobromide;3,4-Thiophenediamine dihydrobromide;3,4-DIAMINOTHIOPHENE;thiophene-3,4-diaMinedihydrochloride;thiophene-3,4-diamine HCl;3,4-DIAMINOTHIOPHENE(WXG03192)
• CAS NO: 78637-85-1
• Molecular Formula: C₄H₆N₂S
• Molecular Weight: 275.99
• Product Categories: Metal Isotopes;Sulfur & Selenium Compounds
• Mol File: 78637-85-1.mol
• Article Data: 16

Chemical Properties

• Melting Point: 150 °C
• Boiling Point: 385.5°C at 760 mmHg
• Flash Point: 186.9°C
• Appearance: /
• Density: 1.367±0.06 g/cm3(Predicted)
• Vapor Pressure: 2.55E-06mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.13±0.10(Predicted)
• CAS DataBase Reference: 3,4-Diaminothiophene dihydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Diaminothiophene dihydrobromide(78637-85-1)
• EPA Substance Registry System: 3,4-Diaminothiophene dihydrobromide(78637-85-1)

Safety Data

• Hazard Codes: Xn
• Statements: 39-20/21/22
• Safety Statements: 24/25
• Hazardous Substances Data: 78637-85-1(Hazardous Substances Data)

Usage

Chemical Properties

Light Brown Solid

InChI:InChI=1/C4H6N2S.2ClH/c5-3-1-7-2-4(3)6;;/h1-2H,5-6H2;2*1H

Upstream product

• 52431-30-8 2,5-dibromo-3,4-dinitrothiophene 
• 90069-81-1 thiophene-3,4-diamine dihydrochloride 
• 3141-26-2 3,4-dibromothiophene 

Downstream Products

• 90069-84-4 N,N'-thiophenediyl-3,4 dibenzamide 
• 272-43-5 thieno<3,4-b>pyrazine 
• 90070-12-5 phenyl-2 thieno<3,4-b>pyrazine 
• 146058-82-4 2,3-dihexylthieno<3,4-b>pyrazine 
• 106944-19-8 2,5-Bis-phenylselanyl-thiophene-3,4-diamine 
• 143810-66-6 1,3-dihydro-4-phenyl-2H-thieno<3,4-b><1,4>diazepin-2-one 
• 106944-38-1 3,4-diamino-2,5-dibenzylthiophene 
• 90070-22-7 3H diphenyl-2,4 thieno<3,4-b>diazepine-1,4 
• 78648-59-6 dimethyl-2,3 thieno<3,4-b>pyrazine 
• 90069-89-9 N,N'-thiophenediyl-3,4 bis-p-toluenesulfonamide 
• 90070-13-6 diphenyl-2,3 thieno<3,4-b>pyrazine 
• 90070-20-5 3H methyl-2 phenyl-4 thieno<3,4-b>diazepine-1,4 
• 632334-68-0 2-chloromethyl-1H-thieno[3,4-d]imidazole 

Relevant articles and documents

Synthesis and characterization of new 2,3-disubstituted thieno[3,4-b]pyrazines: Tunable building blocks for low band gap conjugated materials

(Chemical Equation Presented) Synthetic methods have been developed for the preparation of new 2,3-dihalothieno[3,4-b]pyrazines, from which a variety of new 2,3-difunctionalized thieno[3,4-b]pyrazines have been produced as precursors to conjugated materials. Structural, electronic, and optical characterization of these new analogues illustrate the extent to which the electronic nature of the functional groups can be used to tune the electronic properties of the thieno[3,4-b]pyrazine unit.

THIENODIAZEPINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to novel thienodiazepine derivatives or pharmaceutically acceptable salts thereof, and a pharmaceutical composition including the same. The thienodiazepine derivatives or pharmaceutically acceptable salts thereof exhibit selective inhibition activities against protein kinases such as c-Kit, FLT3, FMS, LYN, RAF1, VEGFR3, PDGFRa, PDGFRb, RET, etc., and thus can be used as a pharmaceutical composition for prevention or treatment of abnormal cell growth diseases.

Homogenous bimetallic catalysis on amination of ArX and ArX2 in aqueous medium-synergistic effect of dicopper complexes

A dicopper complex [Cu2(bpnp)(OH)(CF3COO) 3] (1) (bpnp = 2,7-bis(pyridin-2-yl)-l,8-naphthyridine) was found to be an excellent catalyst on amination of aryl halides and aryl dihalides with ammonia in aqueous solutions leading to the corresponding anilines and aryldiamines, respectively. Catalytic activity of 1 toward amination appears to be superior to those of other mono nuclear copper complexes. Furthermore, the bimetallic catalyst 1 gave exclusively diamination product in the reaction of ArX2 with ammonia, but other copper complexes showed poor selectivity. Kinetic product distribution study suggests that the dicopper metal ions in this catalysis promote the second amination efficiently.