78674-40-5

Basic information

• Product Name: glycyl-N-methyl-L-phenylalaninamide, hydrochloride
• CAS NO: 78674-40-5
• Molecular Weight: 271.747
• Mol File: 78674-40-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: glycyl-N-methyl-L-phenylalaninamide, hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: glycyl-N-methyl-L-phenylalaninamide, hydrochloride(78674-40-5)
• EPA Substance Registry System: glycyl-N-methyl-L-phenylalaninamide, hydrochloride(78674-40-5)

Safety Data

• Hazardous Substances Data: 78674-40-5(Hazardous Substances Data)

Upstream product

• 6206-42-4 N-benzyloxycarbonylglycyl-L-phenylalanine methyl ester 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Downstream Products

• 110694-68-3 N-<(5,6-dihydro-5,5-dimethyl-2-oxo-3-phenyl-1(2H)-pyrazinyl)acetyl>glycyl-N-methyl-L-phenylalaninamide 

Relevant articles and documents

SYNERGISM BETWEEN STEREOEOLECTRONIC AND STEREOPROTONIC EFFECTS IN THE ENZYMIC PEPTIDE BOND FORMATION

Synergism between stereoprotonic (an inherent preference for protonation/deprotonation in the lone pair direction) and stereoelectronic effects on the formation and breakdown of the tetrahedral intermediate has been demonstrated during the kinetically controlled enzymic aminolysis of specific esters by N-nucleophiles.While both N-methylated and N-unmethylated nucleophiles promote chymotrypsin anilide hydrolysis, the N-methylated nucleophiles do not aminolyse detectably acylchymotrypsin.