78756-27-1Relevant articles and documents
Synthesis and evaluation of anticonvulsant activities of 4-phenylpi-peridin-2-one derivatives
Lei, Kang,Li, Guang-Yong,Li, Xiao-Jing,Liu, Hui,Quan, Zhe-Shan,Wang, Shi-Ben,Wang, Xue-Kun
, p. 713 - 724 (2020/07/03)
Background: Although Antiepileptic Drugs (AEDs) acting on various targets have been applied in the clinic, the efficacy and tolerance of AEDs in the treatment of epilepsy have not significantly improved. Therefore, there is an urgent need to develop some
2-ALKENYL-3-AMINOTHIOPHENE DERIVATIVE AND METHOD FOR PRODUCING THE SAME
-
Page/Page column 9-10; 14-15, (2009/01/24)
Disclosed is a method for commercially producing 2-alkenyl-3-aminothiophene derivatives, which are useful as intermediates for agricultural chemicals, at low cost. Specifically disclosed is a method for introducing alkenyl groups into the 2-position of 3-aminothiophene derivatives by reacting 3-aminothiophene derivatives represented by the general formula (2) below or salts thereof with a ketone represented by the general formula (1) below without using a protecting group. Also specifically disclosed are 2-alkenyl-3-aminothiophene derivatives (3a) to (3d) which are useful as intermediates for agricultural chemicals,