78775-97-0

Basic information

• Product Name: tert-Butylmalonsaeure-bis(2-bromethylester)
• Synonyms: tert-Butylmalonsaeure-bis(2-bromethylester)
• CAS NO: 78775-97-0
• Molecular Weight: 374.07
• Mol File: 78775-97-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-Butylmalonsaeure-bis(2-bromethylester)(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butylmalonsaeure-bis(2-bromethylester)(78775-97-0)
• EPA Substance Registry System: tert-Butylmalonsaeure-bis(2-bromethylester)(78775-97-0)

Safety Data

• Hazardous Substances Data: 78775-97-0(Hazardous Substances Data)

Upstream product

• 78775-72-1 2-tert-butylmalonyl dichloride 
• 540-51-2 2-bromoethanol 

Relevant articles and documents

Synthesis and Properties of Some tert-Alkylmalonic Acid Derivatives

1,4-Addition of Grignard reagents to the alkylidenemalonic acid derivatives 1-8 affords the tert-alkyl malonic derivatives 9-18.The esters 9-17 give the acids 19-26 and from these the corresponding chlorides 27-34 are obtained.Bromination yields the bromo acids 35-36, the brominated acyl bromide 43, the bromonitrile 44, and the bromoacyl chlorides 37-42.The trimethylsilyl esters 50-52, the bis(2-bromoethyl) esters 53-54, the ethyl ester 14, and the tert-butyl ester 16 are brominated via the corresponding ester enolates giving the bromo esters 45-46 in pure form. - The dealkylation of malonic esters with chlorotrimethylsilane/sodium iodide has been carried out.