788-18-1

Basic information

• Product Name: 6-{[(3-acetylphenyl)amino]methylidene}cyclohexa-2,4-dien-1-one
• CAS NO: 788-18-1
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.2692
• Mol File: 788-18-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 419.9°C at 760 mmHg
• Flash Point: 167.3°C
• Density: 1.289g/cm³
• Vapor Pressure: 2.92E-07mmHg at 25°C
• Refractive Index: 1.709
• CAS DataBase Reference: 6-{[(3-acetylphenyl)amino]methylidene}cyclohexa-2,4-dien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{[(3-acetylphenyl)amino]methylidene}cyclohexa-2,4-dien-1-one(788-18-1)
• EPA Substance Registry System: 6-{[(3-acetylphenyl)amino]methylidene}cyclohexa-2,4-dien-1-one(788-18-1)

Safety Data

• Hazardous Substances Data: 788-18-1(Hazardous Substances Data)

Upstream product

• 99-03-6 1-(3-aminophenyl)ethanone 
• 90-02-8 salicylaldehyde 
• 89-95-2 2-methyl-benzyl alcohol 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Downstream Products

• 463327-13-1 bis(N-3-acetophenylsalicylaldiminato)copper(II) 
• 339557-03-8 (3-acetophenylsalicylaldiminato)acetylacetonato cobalt(II) 
• 339557-01-6 bis-(3-acetophenylsalicylaldiminato)acetylacetonato cobalt(III) 
• 1370225-54-9 C₂₄H₁₉ClN₄O 
• 1590366-83-8 (E)-1-(3-((E)-2-hydroxybenzylideneamino)phenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 1590366-85-0 (E)-1-(3-((E)-2-hydroxybenzylideneamino)phenyl)-3-p-tolylprop-2-en-1-one 

Relevant articles and documents

Polymorphism control in the mechanochemical and solution-based synthesis of a thermochromic Schiff base

Three crystal forms of a thermochromic Schiff base, namely 1-{3-[(2-hydroxy-3-methoxy-benzylidene)-amino]-phenyl}-ethanone, derived from o-vanillin and 3-aminoacetophenone, were obtained by conventional solution-based methods. Two out of the three polymorphs were synthesized by mechanochemical syntheses, under solvent-free conditions. Herein, we report a study of the dependence of the composition of solvent, the crystallization temperature and impurities on the outcome of the synthesis of Schiff base polymorphs. We report the important role of seed crystals in directing the supramolecular organization of the product of a covalent solvent-free reaction towards the intended polymorphic outcome as well. All obtained polymorphs were investigated by means of thermal analysis, single crystal X-ray diffraction, ex situ and in situ powder X-ray diffraction and IR spectroscopy. The polymorphs display interesting and remarkably different molecular packing arrangements governed by C-H?O interactions leading to two-dimensional networks in forms I and III, and a three-dimensional networks in form II.

Design, synthesis and in vitro antimalarial evaluation of new quinolinylhydrazone derivatives

A series of novel quinolinylhydrazones (5a-f) was synthesized by the condensation reaction of 2,6-diaryl-substituted piperidin-4-ones (4a-f) with 7-chloro-4-hydrazinoquinoline (2). Novel quinolinylhydrazones containing Shiff bases 8a-f and 11a-f were obta

Solvent-free syntheses of salicylaldimines assisted by microwave irradiation

A microwave-assisted condensation of salicylaldehyde and aryl amines without solvent were efficiently performed to form a series of salicylaldimines in high yields, which were confirmed by IR, 1H NMR, 13C NMR and elemental analyses. The microwave-assisted condensation provided a convenient environmental-friendship methodology for syntheses of Schiff-base in organic syntheses.