78805-80-8

Basic information

• Product Name: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-(phenylmethyl)-
• CAS NO: 78805-80-8
• Molecular Formula: C13H13NO
• Molecular Weight: 199.252
• Mol File: 78805-80-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-(phenylmethyl)-(78805-80-8)
• EPA Substance Registry System: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-(phenylmethyl)-(78805-80-8)

Safety Data

• Hazardous Substances Data: 78805-80-8(Hazardous Substances Data)

Upstream product

• 38318-60-4 2-benzyl-3-oxo-6-exo-hydroxy-2-azabicyclo<2.2.1>heptane 
• 75409-90-4 2-benzyl-3-oxo-2-azabicyclo<2.2.1>hept-6-exo-yl p-toluenesulfonate 
• 100-39-0 benzyl bromide 
• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 

Downstream Products

• 95936-44-0 2-benzyl-7-anti-bromo-endo,endo-5,6-dihydroxy-2-azabicyclo<2.2.1>heptan-3-one 
• 95936-43-9 2-benzyl-7-bromo-2-azabicyclo<2.2.1>hept-5-en-3-one 
• 141765-42-6 2-benzyl-6-exo-chloro-7-anti-phenylsulfenyl-2-azabicyclo<2.2.1>heptan-3-one 
• 95936-42-8 2-benzyl-6,7-dibromo-2-azabicyclo<2.2.1>heptan-3-one 
• 78805-81-9 2-benzyl-3-oxo-2-azabicyclo<2.2.1>heptane 
• 141765-47-1 2-benzyl-5-exo-bromo-6-endo-phenylselenyl-2-azabicyclo<2.2.1>heptan-3-one 
• 116230-22-9 2-benzyl-2-azabicyclo[2.2.1]heptane 

Relevant articles and documents

An approach to the synthesis of neplanocin A

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Synthesis of Diphenyl Ether Models of Thyroid Hormones. Diphenyl Ethers Linked to the 3-Oxo-2-azabicycloheptane Ring System as Substrates for Conformational Analysis

A series of diphenyl ethers linked to 2-azabicyclooctan-3-ones and 2-azabicycloheptan-3-ones were synthesized as substrates for conformational analysis using the lanthanide shift reagent NMR technique.The materials were prepared by displacement of the exo-6-tosyloxy bicyclic lactam with the corresponding phenoxide which results in formation of the phenyl ether with retention of stereochemistry.This double-inversion process presumably involves anchimeric assistance by the lactam nitrogen.The synthesis and properties of a number of these systems are described.Complete 13C assignments for the series are presented.