78812-64-3 Usage
General Description
2-HYDROXY-1-(4-IODOPHENYL)ETHANONE is a chemical compound with the molecular formula C8H7IO2. It is a derivative of acetophenone, with a hydroxyl group and an iodine atom attached to the phenyl ring. 2-HYDROXY-1-(4-IODOPHENYL)ETHANONE is commonly used as a building block in organic synthesis, and it has potential applications in pharmaceutical and agrochemical industries. Its unique structure and reactivity make it a versatile precursor for the synthesis of various organic compounds. Furthermore, the presence of the iodine atom makes it an important reagent in chemical reactions, contributing to its potential utility in the development of new drug compounds and other industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 78812-64-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,8,1 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 78812-64:
(7*7)+(6*8)+(5*8)+(4*1)+(3*2)+(2*6)+(1*4)=163
163 % 10 = 3
So 78812-64-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H7IO2/c9-7-3-1-6(2-4-7)8(11)5-10/h1-4,10H,5H2
78812-64-3Relevant articles and documents
Dual Role of H2O2 in Palladium-Catalyzed Dioxygenation of Terminal Alkenes
Huang, Jiuzhong,Li, Jianxiao,Zheng, Jia,Wu, Wanqing,Hu, Weigao,Ouyang, Lu,Jiang, Huanfeng
supporting information, p. 3354 - 3357 (2017/07/13)
A palladium-catalyzed, environmentally friendly dioxygenation reaction of simple alkenes has been developed that enabled rapid assembly of valuable α-hydroxy ketones with high atom economy. Notably, control experiments and 18O isotope-labeling experiments established that H2O2 played a dominant dual role in this transformation.
An efficient method for the synthesis of α-hydroxyalkyl aryl ketones
Chen, Chengqun,Feng, Xinghua,Zhang, Guozhen,Zhao, Qin,Huang, Guosheng
experimental part, p. 3205 - 3208 (2009/05/07)
Exposure of alkyl aryl ketones to Oxone/trifluoroacetic anhydride in the presence of a catalytic amount of iodobenzene affords α-hydroxyalkyl aryl ketones in good yield. This method provides an effective and economical entry for the installation of α-hydroxy moieties into ketones and should find wide application in the construction of the α-hydroxy ketone subunit in natural product synthesis.
