78821-57-5

Basic information

• Product Name: (1RS:2SR)-2-methylamino-1-(3.4-dihydroxy-phenyl)-propanol-⁽¹⁾
• CAS NO: 78821-57-5
• Molecular Weight: 197.234
• Mol File: 78821-57-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1RS:2SR)-2-methylamino-1-(3.4-dihydroxy-phenyl)-propanol-⁽¹⁾(CAS DataBase Reference)
• NIST Chemistry Reference: (1RS:2SR)-2-methylamino-1-(3.4-dihydroxy-phenyl)-propanol-⁽¹⁾(78821-57-5)
• EPA Substance Registry System: (1RS:2SR)-2-methylamino-1-(3.4-dihydroxy-phenyl)-propanol-⁽¹⁾(78821-57-5)

Safety Data

• Hazardous Substances Data: 78821-57-5(Hazardous Substances Data)

Upstream product

• 10329-60-9 (+/-)-erythro-α-methylepinephrine 

Relevant articles and documents

(αS)-erythro-α-Methylepinephrine: Preparation and Stereoselective Binding to Adrenergic Receptors in Rat Forebrain

The enantiomers of a number of catecholamines, including (αS)- and (αR)-erythro-α-methylepinephrine, were evaluated for their capacity to compete for binding sites in rat forebrain homogenates with prazosin, a ligand which selectively binds to adrenergic receptors of the α1 subtype. (αR)-erythro-α-Methylepinephrine is devoid of apparent biological activity, but the activity of the αS isomer is substantial.The latter is less active than the endogeneous catecholamines, (R)-norepinephrine and (R)-epinephrine, but the stereospecific competition for prazosin binding sites by the catecholamine isomers with the βR configuration is additional evidence that (αS)-erythro-α-methylepinephrine may be a biologically active metabolite of L-α-methyl-3,4-dihydroxyphenylalanine.