78823-42-4

Basic information

• Product Name: 4-(ethoxycarbonyl)benzanilide
• Synonyms: 4-(ethoxycarbonyl)benzanilide
• CAS NO: 78823-42-4
• Molecular Weight: 269.3
• Mol File: 78823-42-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(ethoxycarbonyl)benzanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(ethoxycarbonyl)benzanilide(78823-42-4)
• EPA Substance Registry System: 4-(ethoxycarbonyl)benzanilide(78823-42-4)

Safety Data

• Hazardous Substances Data: 78823-42-4(Hazardous Substances Data)

Upstream product

• 15226-74-1 dicobalt octacarbonyl 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 62-53-3 aniline 
• 201230-82-2 carbon monoxide 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 38117-54-3 cyclopentadienyl iron(II) dicarbonyl dimer 
• 348-06-1 p-carboethoxybenzenediazonium tetrafluoroborate 
• 78823-37-7 C₁₅H₁₈O₅ 

Relevant articles and documents

Cobalt carbonyl as an effective CO source in one-pot synthesis of esters from aryl halides

For the first time, we have successfully applied Co2(CO) 8 as an effective carbonyl source for the Pd catalysed alkoxycarbonylation of aryl halides affording the corresponding aryl esters under mild microwave conditions. A wide variety of esters and carbonyl derivatives were prepared using this protocol.

Bis(cyclopentadienyldicarbonyliron) as a convenient carbon monoxide source in palladium-catalyzed carbonylative coupling of aryl iodides with amines, alcohols, and thiols

Bis(cyclopentadienyldicarbonyliron) ([CpFe(CO)2]2) serves as a carbon monoxide source in carbonylative coupling reactions. Treatment of aryl iodides with primary amines in the presence of DBU and [CpFe(CO)2]2 under palladium catalysis provides the corresponding benzamides in good yields. Similar reactions with phenols and thiols provide the corresponding benzoate esters and thioesters, respectively. A catalytic amount of DMAP as an additive promoted the carbonylative coupling reactions with primary alcohol and secondary amine.