78837-35-1

Basic information

• Product Name: 3-Cyano-4-azahomoadamantane
• Synonyms: 3-Cyano-4-azahomoadamantane
• CAS NO: 78837-35-1
• Molecular Weight: 176.261
• Mol File: 78837-35-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Cyano-4-azahomoadamantane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyano-4-azahomoadamantane(78837-35-1)
• EPA Substance Registry System: 3-Cyano-4-azahomoadamantane(78837-35-1)

Safety Data

• Hazardous Substances Data: 78837-35-1(Hazardous Substances Data)

Upstream product

• 24886-73-5 1-Azidoadamantane 
• 151-50-8 potassium cyanide 
• 143-33-9 sodium cyanide 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 78822-98-7 4-Oxo-5-phenyl-5,7-diazatetracyclo<7.3.1.1^3,11.0^3,7>tetradecan-6-thione 
• 78822-97-6 5-Phenyl-5,7-diazatetracyclo<7.3.1.1^3,11.0^3,7>tetradecan-4,6-dione 
• 78822-96-5 4-Imino-5-phenyl-5,7-diazatetracyclo<7.3.1.1^3,11.0^3,7>tetradecan-6-thione 
• 78822-94-3 4-Imino-5-phenyl-5,7-diazatetracyclo<7.3.1.1^3,11.0^3,7>tetradecan-6-one 

Relevant articles and documents

Synthesis of Adamantane Derivatives. 54. Synthesis of Novel 4-Azahomoadamantano-Fused Heterocycles via Hydrocyanation of 4-Azahomoadamant-3-ene

Photolysis of 1-azidoadamantane (1) in an aqueous NaCN-n-hexane two-phase system with Adogen 464 as a phase-transfer catalyst gave 3-cyano-4-azahomoadamantane (3), a hydrocyanation product of 4-azahomoadamant-3-ene (2).AlCl3-catalyzed decomposition of 1 in the presence of trimethylsilyl cyanide also afforded 3. 3 gave the corresponding amino acid 6 and its ester 7. 4-Azahomoadamantano-fused hydantoin, iminohydantoin, iminothiohydantoin, and thiohydantoin, 12-17, were readily prepared by the reactions of 3 with appropriate isocyanates and isothiocyanates.The reactions of 3 with dimethyl acetylenedicarboxylate, methyl vinyl ketone, and diketene afforded the corresponding iminopyrroline (20), aminopyrroline (23), and aminopyrrolinone (26).Acetylation of 3 gave N-acetylamino derivative 27, which was converted to Δ2-oxazolinium perchlorate 30 via N-acetylamino acid 29.