78939-34-1

Basic information

• Product Name: 2-METHOXY-5-AMINOFORMANILIDE
• Synonyms: 2-METHOXY-5-AMINOFORMANILIDE;N-(5-AMino-2-Methoxyphenyl)forMaMide
• CAS NO: 78939-34-1
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• Product Categories: Aromatics Compounds;Aromatics;Amines
• Mol File: 78939-34-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly)
• CAS DataBase Reference: 2-METHOXY-5-AMINOFORMANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-5-AMINOFORMANILIDE(78939-34-1)
• EPA Substance Registry System: 2-METHOXY-5-AMINOFORMANILIDE(78939-34-1)

Safety Data

• Hazardous Substances Data: 78939-34-1(Hazardous Substances Data)

Usage

Description

2-Methoxy-5-aminoformanilide, with the chemical name 2-methoxy-5-amino-N-phenylformamide and CAS number 78939-34-1, is a white crystalline solid. It is a compound that is useful in organic synthesis, particularly for the production of various organic compounds and pharmaceuticals.

Uses

Used in Organic Synthesis:
2-Methoxy-5-aminoformanilide is used as a key intermediate in the synthesis of various organic compounds. Its unique chemical structure allows it to be a versatile building block for the development of new molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methoxy-5-aminoformanilide is used as a starting material for the synthesis of various drug candidates. Its presence in the molecular structure can contribute to the desired pharmacological properties, such as improved solubility, stability, and bioavailability.
Used in Chemical Research:
2-Methoxy-5-aminoformanilide is also used in chemical research for the investigation of new synthetic routes and the development of novel chemical reactions. Its unique properties make it an interesting subject for studying the reactivity and selectivity of various chemical transformations.

Upstream product

• 149686-06-6 N-(2-methoxyl-5-nitrophenyl)formamide 
• 99-59-2 3-amino-4-methoxynitrobenzene 

Downstream Products

• 107575-59-7 ethyl pyruvate 3-formamido-4-methoxyphenyl-hydrazone 
• 119825-21-7 3-Formylamino-4-methoxy-benzenediazonium; chloride 
• 80721-47-7 4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester 
• 72909-34-3 pyrroloquinoline quinone 
• 119825-27-3 6-(Formylamino)-5-methoxyindol-2-carbonsaeure-ethylester 
• 107575-60-0 6-amino-5-methoxy-2-ethoxycarbonylindole 
• 133706-80-6 5-Methoxy-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester 

Relevant articles and documents

Pyrroloquinoline quinone synthetic method

The invention discloses a synthetic method of pyrroloquinoline quinone. The synthetic method comprises the following steps: carrying out alkali treatment on 2-methoxy-5-nitroaniline hydrochloride as a raw material, so as to obtain a compound 1; carrying out formylation on the compound 1 under a catalysis condition of an ionic liquid, so as to obtain a compound 2; adopting sodium borohydride to reduce the compound 2 to obtain a compound 3; carrying out diazotization on the compound 3, and then enabling action between the diazotized compound 3 and HBF4 to obtain a compound 4; enabling reaction of the compound 4 and 2-methylethyl acetoacetate to obtain a compound 5; treating the compound 5 with formic acid to obtain a compound 6; carrying out amid catalysis and exchange with the ionic liquid on the compound 6 to obtain a compound 7; enabling reaction of the compound 7 and 2-oxodimethyl glutaconate to obtain a compound 8; feeding hydrogen chloride to the compound 8 under the action of Cu(OAc)2*2H2O to obtain a compound 9; carrying out basic hydrolysis on the compound 9 to obtain a compound 10. The synthetic method disclosed by the invention is cheap and accessible in raw materials, stable, high in reaction yield, quick in reaction, and easy for product separation, and is environment-friendly as the catalyst can be recycled.

SYNTHESIS OF PYRROLOQUINOLINE QUINONE (PQQ)

The invention relates to a novel nine step process for synthesizing PQQ (methoxatin). This process is efficient and reliably provides PQQ in excellent purity and high yield.