78945-64-9

Basic information

• Product Name: 1-phenylpyrrole-3,4-dicarboxylic acid diethyl ester
• Synonyms: 1-phenylpyrrole-3,4-dicarboxylic acid diethyl ester
• CAS NO: 78945-64-9
• Molecular Weight: 287.315
• Mol File: 78945-64-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-phenylpyrrole-3,4-dicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylpyrrole-3,4-dicarboxylic acid diethyl ester(78945-64-9)
• EPA Substance Registry System: 1-phenylpyrrole-3,4-dicarboxylic acid diethyl ester(78945-64-9)

Safety Data

• Hazardous Substances Data: 78945-64-9(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 41969-71-5 diethyl pyrrole-3,4-dicarboxylate 
• 5472-38-8 diethyl 2-formylbutanedioate 
• 70145-29-8 diethyl 2-(diethoxymethyl)succinate 
• 73926-95-1 diethyl 2-formyl-3-(diethoxymethyl)succinate 
• 62-53-3 aniline 
• 39654-83-6 diethyl (2E,3E)-2,3-bis[(dimethylamino)methylidene] succinate 
• 591-50-4 iodobenzene 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 1520-50-9 but-2-enedioic acid diethyl ester 

Downstream Products

• 1422348-26-2 diethyl 1-phenyl-2,5-di(thiophen-2-yl)-1H-pyrrole-3,4-dicarboxylate 
• 78966-72-0 1-fenil-3,4-di(etiltio)carbonilpirrolo 
• 78945-65-0 1-fenil-3,4-diformilpirrolo 
• 78945-63-8 1-fenilpirrolo-3,4-dicarbossilico 

Relevant articles and documents

Nonreaction-based fluorescent Au3+ probe that gives fast response in aqueous solution

The design and synthesis of a simple, selective and efficient turn-off fluorescent Au3+ probe, namely, diethyl 1-phenyl-2,5-di(thiophen-2- yl)-1H-pyrrole-3,4-dicarboxylate (1), are highlighted. To our best knowledge, this is the first example of nonreaction-based fluorescent Au3+ probes.

Practical one-pot sequential procedure for the preparation of N-arylated 3,4-disubstituted pyrroles from alkenes

By using tBuONa and Cs2CO3 as a mixed base, van Leusen pyrrole synthesis and copper-catalyzed N-arylation of pyrrole proceeded sequentially in a single flask to give N-arylated 3,4-disubstituted pyrroles smoothly. Thus, a series of desired N-arylated pyrroles were prepared directly from the electron-deficient alkenes.