78946-48-2Relevant articles and documents
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Crowley,K.J.
, p. 1210 (1963)
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A NOVEL FIVE-CARBON HOMOLOGATION LEADING TO 3,4-ALKADIENOIC ACIDS BY SN2' REACTION OF β-ETHYNYL-β-PROPIOLACTONE WITH GRIGNARD REAGENTS IN THE PRESENCE OF COPPER(I) CATALYST
Sato, Toshio,Kawashima, Masatoshi,Fujisawa, Tamotsu
, p. 2375 - 2378 (2007/10/02)
β-Ethynyl-β-propiolactone reacts regioselectively with Grignard reagents in the presence of copper(I) catalyst to afford 3,4-alkadienoic acids in high yields.Synthetic utility of this reaction is demonstrated in the simple synthesis of pellitorine.