79-61-8 Usage
Originator
Diloderm ,Schering,US,1960
Uses
antipruretic
Manufacturing Process
A solution of 1.0 g of 1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione-21-
acetate and 5.0 g of lithium chloride in 40 ml of glacial acetic acid is treatedwith 0.410 g of N-chlorosuccinimide, followed by 0.104 g of anhydrous
hydrogen chloride dissolved in 2.5 ml of tetrahydrofuran. The reaction mixture
is stirred for 2 hours and poured into ice water. The crude product is filtered
and washed with water to give 1.12 g of solid material, which is recrystallized
from acetone-hexane to give substantially pure 9α,11β-dichloro-1,4-
pregnadiene-17α,21-diol-3,20-dione-21-acetate; MP 246°C to 253°C (dec.).
Brand name
Diloderm (Schering).
Therapeutic Function
Antipruritic, Antihistaminic, Appetite stimulant
Check Digit Verification of cas no
The CAS Registry Mumber 79-61-8 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 79-61:
(4*7)+(3*9)+(2*6)+(1*1)=68
68 % 10 = 8
So 79-61-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H28Cl2O5/c1-13(26)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(27)6-8-20(14,2)23(17,25)18(24)11-21(16,22)3/h6,8,10,16-18,29H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
