79037-17-5

Basic information

• Product Name: (20S,22R,25R)-1α,3β-dihydroxyspirost-5-ene
• Synonyms: (20S,22R,25R)-1α,3β-dihydroxyspirost-5-ene
• CAS NO: 79037-17-5
• Molecular Weight: 430.628
• Mol File: 79037-17-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (20S,22R,25R)-1α,3β-dihydroxyspirost-5-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (20S,22R,25R)-1α,3β-dihydroxyspirost-5-ene(79037-17-5)
• EPA Substance Registry System: (20S,22R,25R)-1α,3β-dihydroxyspirost-5-ene(79037-17-5)

Safety Data

• Hazardous Substances Data: 79037-17-5(Hazardous Substances Data)

Upstream product

• 87425-36-3 ruscogenin 3-O-β-D-glucopyranosyl(1->3)-α-L-rhamnopyranoside 
• 38971-41-4 25(S)-ruscogenin 1-O-α-L-rhamnopyranosyl-(1->2)-β-D-fucopyranoside 
• 87425-34-1 25(S)-ruscogenin 1-O-β-D-fucopyranosido-3-O-α-L-rhamnopyranoside 
• 105798-62-7 alliofuroside A 
• 39491-38-8 alliospiroside A 
• 105822-00-2 22-O-methyl ether of alliofuroside A 
• 87436-70-2 25(S)-ruscogenin 3-O-L-rhamnopyranoside 
• 87436-70-2 ruscogenin 3-O-α-L-rhamnopyranoside 
• 1072072-38-8 (25R)-1α-hydroxyspirost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1->2)-[O-α-L-rhamnopyranosyl(1->4)]-β-D-glucopyranoside 
• 472-11-7 (25R)-ruscogenin 
• 90802-64-5 3β-acetoxyspirost-5-ene-1-one 
• 14414-62-1 spirost-5-ene-1-oxo-3β-ol 
• 17676-33-4 spirosta-5(6),25(27)-diene-1β,3β-diol 
• 512-04-9 diosgenin 

Downstream Products

• 861675-03-8 Toluene-4-sulfonic acid (R)-4-((2R,4S,4aR,4bS,6aS,6bS,9aS,10aR)-2,4-dihydroxy-4a,6a,7-trimethyl-2,3,4,4a,4b,5,6,6a,6b,9a,10,10a-dodecahydro-1H-9-oxa-pentaleno[2,1-a]phenanthren-8-yl)-2-methyl-butyl ester 
• 35882-30-5 25(S) ruscogenin 
• 6155-50-6 25(S)-ruscogenin 1,3-diacetate 
• 6155-50-6 25(S)-ruscogenin diacetate 

Relevant articles and documents

New steroidal glycosides from rhizomes of Clintonia udensis

A total of 10 steroidal glycosides, together with three new spirostanol glycosides (6-8), a new furostanol glycoside (9), and a new cholestane glycoside (10), were isolated from the rhizomes of Clintonia udensis (Liliaceae). The structures of the new compounds were determined on the basis of extensive spectroscopic analyses, including 2-D nuclear magnetic resonance (NMR) data, and of hydrolytic cleavage followed by chromatographic or spectroscopic analyses. The isolated glycosides were evaluated for their cytotoxic activity against HL-60 leukemia cells. Spirostanol glycosides 1 and 2, and furostanol glycoside 4 showed cytotoxic activity with IC50 values of 3:2 ± 0:02, 2:2 ± 0:12, and 2:2 ± 0:06 μg/ml, respectively. Neither the spirostanol and furostanol saponins with a hydroxy group at C-1 (6 and 9) and C-12 (7 and 8) nor cholestane glycosides (5 and 10) exhibited apparent cytotoxic activity at a sample concentration of 10μg/ml.

Synthesis of (25R)-ruscogenin-1-yl β-D-xylopyranosyl-(1→3)- [β-D-glucopyranosyl-(1→2)]-β-D-fucopyranoside

The synthesis of (25R)-ruscogenin-1-yl β-D-xylopyranosyl-(1→3)- [β-D-glucopyranosyl-(1→2)]-β-D-fucopyranoside, a saponin from the tuber of Liriope muscari (Decne.) Bailey, is described.

Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. I. Studies of the Constituents of the Subterranean Part of Liriope platyphylla Wang et Tang.

Eight steroidal glycosides, tentatively named glycosides A(1), B(2), C(3), D(4), E(5), F(6), G(7) and H(8), were isolated from the methanol extract of the subterranean part of Liriope platyphylla Wang et Tang (Liliaceae).The structures of these glycosides were established as ruscogenin 3-O-α-L-rhamnopyranoside (1), 25(S)-ruscogenin 1-O-β-D-fucopyranosido-3-O-α-L-rhamnopyranoside (2), 25(S)-ruscogenin 1-O-α-L-rhamnopyranosyl-(1->2)-β-D-fucopyranoside (3), ruscogenin 3-O-β-D-glucopyranosyl(1->3)-α-L-rhamnopyranoside (4), a mixture of 3-O-2)>3)>-β-D-glucopyranosides of diosgenin and yamogenin (=a mixture of ophiopogonin D' and its 25(S)-isomer, 5), a mixture of 3-O-β-chacotriosides of diosgenin and yamogenin (= a mixture of dioscin and its 25(S)-isomer, 6), ruscogenin 1-sulfate 3-O-α-L-rhamnopyranoside (7), and 26-O-β-D-glucopyranosyl-22-O-methylfurost-5-ene-3β,26-diol 3-O-β-chacotrioside (=methyl proto-dioscin, 8).