79055-59-7

Basic information

• Product Name: 2-bromo-6-methylpyridin-4-amine
• Synonyms: 2-bromo-6-methylpyridin-4-amine;4-Amino-2-bromo-6-methylpyridine;2-bromo-6-methyl-4-Pyridinamine;2-Bromo-6-methylpyridin-4-ylamine;2-Bromo-6-methylpyridin-4-amine, 4-Amino-6-bromo-2-picoline;4-Amino-2-bromo-6-methylpyridin
• CAS NO: 79055-59-7
• Molecular Formula: C₆H₇BrN₂
• Molecular Weight: 187.03718
• Mol File: 79055-59-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 179 °C(Solv: benzene (71-43-2))
• Boiling Point: 312.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.593±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 5.55±0.50(Predicted)
• CAS DataBase Reference: 2-bromo-6-methylpyridin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-6-methylpyridin-4-amine(79055-59-7)
• EPA Substance Registry System: 2-bromo-6-methylpyridin-4-amine(79055-59-7)

Safety Data

• Hazardous Substances Data: 79055-59-7(Hazardous Substances Data)

Usage

General Description

2-bromo-6-methylpyridin-4-amine is a chemical compound with the molecular formula C6H7BrN2. It is an organic compound with a pyridine ring that contains a bromine atom and a methyl group. 2-bromo-6-methylpyridin-4-amine is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure makes it a useful intermediate for the production of various compounds with biological activities. 2-bromo-6-methylpyridin-4-amine is an important reagent in organic chemistry and has applications in medicinal and agricultural chemistry.

Upstream product

• 79055-52-0 2,4-dibromo-6-methylpyridine 
• 60323-99-1 2-bromo-6-methyl-4-nitro-pyridine-1-oxide 
• 91668-84-7 2-bromo-6-methylpyridine N-oxide 
• 5315-25-3 2-bromo-6-methylpyridine 

Downstream Products

• 524717-70-2 2-(3,4-dihydro-1H-isoquinolin-2-yl)-6-methyl-pyridin-4-yl-amine 
• 524717-76-8 N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-6-methyl-pyridin-4-yl]-oxalamic acid ethyl ester 
• 521917-30-6 2-(7-Chloro-3,4-dihydro-naphthalen-2-yl)-6-methyl-pyridin-4-yl-amine fumarate 
• 614752-47-5 4-fluoro-6-methyl-2-pyridinecarboxaldehyde 
• 99233-21-3 (4-amino-6-methylpyridin-2-yl)methanol 

Relevant articles and documents

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Arylmethoxypyridines as novel, potent and orally active mGlu5 receptor antagonists

Optimisation of affinity, chemical stability, metabolic stability and solubility led from a chemically labile HTS hit 1 to mGlu5 receptor antagonists (24-26) with high affinity for the allosteric MPEP binding site, improved microsomal metabolic stability and anxiolytic-like activity in vivo as assessed by the Vogel conflict drinking test.

4-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines and 4-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinolines as potent NR1/2B subtype selective NMDA receptor antagonists

A series of 4-(3,4-dihydro-1H-isoquinolin-2yl)-pyridines and analogous quinolines was prepared and evaluated as NR1/2B subtype selective NMDA receptor antagonists. 2-Hydroxyalkylamino substitution combines high affinity with selectivity (vs α1 and M1 receptors) and activity in vivo.