79100-16-6

Basic information

• Product Name: METHYL 2-(2-FORMYL-1H-PYRROL-1-YL)BENZOATE
• Synonyms: METHYL 2-(2-FORMYL-1H-PYRROL-1-YL)BENZOATE;2-(2-FORMYL-PYRROL-1-YL)-BENZOIC ACID METHYL ESTER
• CAS NO: 79100-16-6
• Molecular Formula: C₁₃H₁₁NO₃
• Molecular Weight: 229.23
• Mol File: 79100-16-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 2-(2-FORMYL-1H-PYRROL-1-YL)BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-(2-FORMYL-1H-PYRROL-1-YL)BENZOATE(79100-16-6)
• EPA Substance Registry System: METHYL 2-(2-FORMYL-1H-PYRROL-1-YL)BENZOATE(79100-16-6)

Safety Data

• Hazardous Substances Data: 79100-16-6(Hazardous Substances Data)

Upstream product

• 10333-67-2 methyl 2-(1H-pyrrol-1-yl)benzoate 
• 68-12-2 N,N-dimethyl-formamide 
• 65057-97-8 tetrahydro-2,5-dimethoxy-2-furaldehyde dimethyl acetal 
• 134-20-3 2-carbomethoxyaniline 
• 610-97-9 o-iodo-methyl-benzoic acid 

Downstream Products

• 79100-17-7 N-(2-hydroxymethylphenyl)-2-hydroxymethylpyrrole 
• 79100-19-9 6-oxo-4H-pyrrolo<1,2-a><4,1>benzoxazepine 
• 101130-76-1 4-hydroxy-4H,6H-pyrrolo<1,2-a><4,1>benzoxazepine 
• 92508-14-0 1-(2-metossicarbonilfenil)pirrolo-2-carbaldossima 
• 39243-92-0 4,5-diidro-6H-pirrolo<1,2-a><1,4>benzodiazepina 
• 1095362-17-6 5-(3,4-dimethoxybenzyl)-4,5-dihydro-6H-pyrrolo[1,2-a][1,4]benzodiazepin-6-one 
• 1095362-30-3 5-(3,4-dimethoxybenzyl)-5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepine 
• 1095362-06-3 C₂₂H₂₄N₂O₄ 

Relevant articles and documents

MODULAR SYNTHESES OF DISCOIPYRROLE TYPE ALKALOIDS AND ANALOGUES

The present invention relates to methods for preparing a variety of discoipyrrole compounds and analogues using an oxidative cyclisation reaction as one of the steps. The present invention also relates to novel discoipyrrole analogues, pharmaceutical comp

New method of synthesis of 5,6-dihydro-4H-pyrrolo[1,2-a]-[1,4] benzodiazepines

2,5-Dimethoxy-2-(dimethoxymethyl)tetrahydrofuran 1 reacted with anthranilic acid alkyl esters 2 in boiling acetic acid to give 2-(2-formylpyrrol-1-yl) benzoic acid esters 3. The reductive amination of 3 with primary arylalkylamines 4 led to 2-{2-[(arylalkylamino)methyl]pyrrol-1-yl}-benzoic acids esters 5. Heating of the aminoesters 5 in xylene under reflux resulted in 5-(arylalkyl)-4,5-dihydro-6H-pyrrolo[1,2-a][1,4]benzodiazepin-6-ones 7. Lactams 7 were reduced by lithium aluminum hydride in toluene and and ether solutions to give 5-(arylalkyl)-5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepines 8. The solid products 8 were recrystallized and the liquid ones were transformed into their salts with oxalic acid. The Japan Institute of Heterocyclic Chemistry.