791124-54-4

Basic information

• Product Name: 10-O-hexadecyl-1-p-toluenesulfonyloxydecane
• Synonyms: 10-O-hexadecyl-1-p-toluenesulfonyloxydecane
• CAS NO: 791124-54-4
• Molecular Weight: 552.903
• Mol File: 791124-54-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 10-O-hexadecyl-1-p-toluenesulfonyloxydecane(CAS DataBase Reference)
• NIST Chemistry Reference: 10-O-hexadecyl-1-p-toluenesulfonyloxydecane(791124-54-4)
• EPA Substance Registry System: 10-O-hexadecyl-1-p-toluenesulfonyloxydecane(791124-54-4)

Safety Data

• Hazardous Substances Data: 791124-54-4(Hazardous Substances Data)

Upstream product

• 112-47-0 1,10-Decanediol 
• 791124-52-2 10-O-hexadecyl-1-tetrahydropyranyloxydecane 
• 43047-93-4 10-tetrahydropyranyloxydecanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 791124-53-3 10-O-hexadecyl-1-decanol 

Downstream Products

• 791124-55-5 (2R,3R,4S,5R)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-(10-hexadecyloxy-decane-1-sulfonylmethyl)-tetrahydro-furan 

Relevant articles and documents

Sulfone and phosphinic acid analogs of decaprenolphosphoarabinose as potential anti-tuberculosis agents

Mycobacteria biosynthesize a cell wall structure that is rich in polysaccharides containing arabinofuranose residues. The source of these arabinofuranose residues is decaprenolphosphoarabinose (1), the donor substrate for mycobacterial arabinosyltransferases. We have previously demonstrated that an analog of 1, C-phosphonate 7, prevented the growth of mycobacteria and this compound is currently undergoing testing for efficacy in tuberculosis-infected mice. We describe here the synthesis and testing of additional analogs of 1 that contain either a sulfone (8-14) or phosphinic acid (15-19) moiety in place of the phosphodiester functionality. Screening of these compounds in vitro against Mycobacterium tuberculosis strain H37Rv revealed that while some of these compounds possessed low to modest activity, none was as potent as 7.