79139-61-0Relevant articles and documents
PYRAZOLONE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR AGONISTS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
-
Page/Page column 299; 300, (2008/06/13)
Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, X, and n are as defined for Formula (I) in the description, processes for the preparation of the compounds and new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and the use of the compounds in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction.
Diaza-spiropiperidine derivatives
-
Page/Page column 8, (2010/02/12)
The present invention relates to compounds of formula wherein A—B, R1, R2, R3, R4, and n are as defined herein; and to pharmaceutically acceptable salts thereof. The compounds of formula I may be used in the tre
THE SYNTHESIS OF 1-PHENYL-3,8-DIAZASPIRODECANES
Parys, Marc Van,Vandewalle, Maurits
, p. 757 - 766 (2007/10/02)
The synthesis of some substituted 3,8-diazaspirodecanes is described.Two routes starting from 1-benzyl-4-oxo-piperidine have been explored.The title compounds are isosteric to the 1,3,8-triazaspirodecane structure present in important neuroleptic agents.