79271-24-2Relevant articles and documents
Synthesis of cinnolines via Rh(III)-catalysed dehydrogenative C-H/N-H functionalization: Aggregation induced emission and cell imaging
Mayakrishnan, Sivakalai,Arun, Yuvaraj,Balachandran, Chandrasekar,Emi, Nobuhiko,Muralidharan, Doraiswamy,Perumal, Paramasivan Thirumalai
, p. 1958 - 1968 (2016)
Rhodium catalysed dehydrogenative C-H/N-H functionalization was developed to construct phthalazino[2,3-a]-/indazolo[1,2-a]cinnolines by reacting N-phenyl phthalazine/indazole with alkynes. The synthesized compounds exhibit prominent fluorescence properties in solid and aggregation states. Their application in cell imaging was investigated using various cancer cell lines.
An efficient synthesis of 1-arylindazole-3-carboxamides using nitrile imines, isocyanides and 2-hydroxymethylbenzoic acid, followed by a chemoselective Buchwald-Hartwig intramolecular cyclization
Giustiniano,Mercalli,Novellino,Tron
, p. 34913 - 34920 (2016/05/09)
A convergent and efficient two-step synthesis of pharmaceutically relevant 1-arylindazole-3-carboxamides is reported. These molecules have been obtained in good to excellent yields (up to 98%) starting from a strategic reaction between isocyanides, 2-iodo