792884-63-0

Basic information

• Product Name: ((S)-3-Amino-2-oxo-piperidin-1-yl)-acetic acid benzyl ester
• CAS NO: 792884-63-0
• Molecular Weight: 262.309
• Mol File: 792884-63-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((S)-3-Amino-2-oxo-piperidin-1-yl)-acetic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((S)-3-Amino-2-oxo-piperidin-1-yl)-acetic acid benzyl ester(792884-63-0)
• EPA Substance Registry System: ((S)-3-Amino-2-oxo-piperidin-1-yl)-acetic acid benzyl ester(792884-63-0)

Safety Data

• Hazardous Substances Data: 792884-63-0(Hazardous Substances Data)

Upstream product

• 175133-83-2 (3S)-benzyl 2-(3-((tert-butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetate 
• 74411-97-5 3(S)-[(tert-butyloxycarbonyl)amino]-2-oxo-1-piperidineacetic acid 
• 74411-96-4 N^α-(tert-butoxycarbonyl)-N^δ-(carboxymethyl)ornithine 
• 2480-93-5 Boc-Orn(Z)-OH 

Downstream Products

• 174960-81-7 (S)-(2-oxo-3-phenylmethanesulfonyl-piperidiny-1-yl)acetic acid 
• 797752-43-3 ((S)-2-Oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetic acid benzyl ester 

Relevant articles and documents

Design, synthesis, and structure-activity relationships of unsubstituted piperazinone-based transition state factor Xa inhibitors

A series of novel transition state factor Xa inhibitors containing a variety of lactam ring systems as central templates was synthesized in an expedient manner and allowed for a great deal of structural variability. Among them, the piperazinone-based inhibitors were found to be not only active against factor Xa but also selective over thrombin. Optimization of the P4 moiety yielded several potent compounds with IC50 below 1 nM against factor Xa.