79293-84-8 Usage
General Description
N-(tert-butyldimethylsilyl)phthalimide is an organosilicon compound used as a reagent in organic synthesis. It is a colorless solid that is soluble in organic solvents. N-(TERT-BUTYLDIMETHYLSILYL)PHTHALIMIDE is commonly used in the protection of amines during chemical reactions and as a precursor for the synthesis of various organic compounds. The tert-butyldimethylsilyl (TBS) group serves as a protecting group for amines, allowing for selective manipulation of other functional groups in the molecule. N-(tert-butyldimethylsilyl)phthalimide is a valuable tool for the preparation of complex organic molecules in a controlled and efficient manner.
Check Digit Verification of cas no
The CAS Registry Mumber 79293-84-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,2,9 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 79293-84:
(7*7)+(6*9)+(5*2)+(4*9)+(3*3)+(2*8)+(1*4)=178
178 % 10 = 8
So 79293-84-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO2Si/c1-14(2,3)18(4,5)15-12(16)10-8-6-7-9-11(10)13(15)17/h6-9H,1-5H3
79293-84-8Relevant articles and documents
Strong influence of intramolecular Si?O proximity on reactivity: Systematic molecular structure, solvolysis, and mechanistic study of cyclic N-trimethylsilyl carboxamide derivatives
Szalay, Roland,Harmat, Veronika,E?ri, János,Pongor, Gábor
supporting information, p. 2186 - 2192 (2017/05/16)
A comparative alcoholysis study of N-silylated derivatives of simple heterocyclic carboxamides (lactams, imides, ureas) is presented. The second-order rate constant values span a range as wide as three orders of magnitude. On the basis of DFT calculations, a good correlation between reactivity and the Si?O distance was found within each family of compounds. The viability of two different reaction pathways was evaluated using a detailed computational mechanistic study of the methanolysis of cyclic urea homologues. Peculiarities in the single-crystal X-ray diffraction structures of the trimethylsilyl and trimethylsiloxy phthalimides are also discussed.
O-Silylated Ketene Acetal Chemistry; A Mild and Efficient t-Butyldimethylsilylating Agent
Kita, Yasuyuki,Haruta, Jun-ichi,Fujii, Takehiko,Segawa, Jun,Tamura, Yasumitsu
, p. 451 - 452 (2007/10/02)
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