79370-70-0Relevant articles and documents
Solid-phase selenium-catalyzed selective allylic chlorination of polyprenoids: Facile syntheses of biologically active terpenoids
Barrero, Alejandro F.,Del Moral, Jose F. Quilez,Herrador, M. Mar,Cortes, Manuel,Arteaga, Pilar,Catalan, Julieta V.,Sanchez, Elena M.,Arteaga, Jesus F.
, p. 5811 - 5814 (2007/10/03)
Regioselective halogenation of the terminal isopropylidene unit of different acyclic polyolefinic polyprenoids (farnesyl acetate, geranylgeranyl acetate, squalene, etc.) using NCS/catalytic polymer-supported selenenyl bromide is described; good to excellent yields are obtained (68-96%). The first applications of this protocol include the concise synthesis of bioactive terpenoids 1-3.