79371-66-7

Basic information

• Product Name: 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol
• CAS NO: 79371-66-7
• Molecular Formula: C₁₅H₁₆O₃
• Molecular Weight: 244.2857
• Mol File: 79371-66-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 449.2°C at 760 mmHg
• Flash Point: 218°C
• Density: 1.233g/cm³
• Vapor Pressure: 1.1E-08mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol(79371-66-7)
• EPA Substance Registry System: 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol(79371-66-7)

Safety Data

• Hazardous Substances Data: 79371-66-7(Hazardous Substances Data)

Usage

Description

4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol, also known as dihydroxyphenethylbenzene, is a chemical compound with the molecular formula C17H18O3. It is a derivative of benzene and contains two hydroxyl groups and a substituted side chain. 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol has been shown to possess antioxidant and anti-inflammatory properties, making it potentially useful for medicinal purposes. Additionally, it has been studied for its potential role in the treatment of neurodegenerative diseases due to its ability to protect against oxidative stress.

Uses

Used in Pharmaceutical Industry:
4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its antioxidant and anti-inflammatory properties make it a valuable component in the development of new medications.
Used in Medicinal Applications:
4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol is used as a potential therapeutic agent for neurodegenerative diseases. Its ability to protect against oxidative stress makes it a promising candidate for the treatment of conditions such as Alzheimer's disease, Parkinson's disease, and other related disorders.
Used in Antioxidant Formulations:
Due to its antioxidant properties, 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol can be used in the formulation of antioxidant supplements and nutraceuticals to support overall health and well-being.
Used in Anti-inflammatory Agents:
The anti-inflammatory properties of 4-[2-(4-hydroxyphenyl)propan-2-yl]benzene-1,2-diol make it suitable for use in the development of anti-inflammatory agents, which can be beneficial in treating various inflammatory conditions and pain management.

Upstream product

• 80-05-7 BPA 
• 163405-36-5 4-(2-(4-hydroxyphenyl)propan-2-yl)cyclohexa-3,5-diene-1,2-dione 
• 70-18-8 GLUTATHIONE 

Downstream Products

• 163405-36-5 4-(2-(4-hydroxyphenyl)propan-2-yl)cyclohexa-3,5-diene-1,2-dione 

Relevant articles and documents

Characterization of new bisphenol A metabolites produced by CD1 mice liver microsomes and S9 fractions

Bisphenol A [2,2-bis(4-hydroxyphenyl)propane] (BPA) is a widely used industrial chemical resulting in occupational and consumer exposure. BPA possesses weak estrogenomimetic activity and can be cytotoxic, though the underlying mechanisms of its toxicity toward cells are not completely understood. The metabolism of BPA by CD1 mice liver microsomal and S9 fractions was investigated. Nine metabolites were isolated and characterized using HPLC and mass spectrometry. Many of these metabolites were characterized for the first time in mammals, namely isopropyl-hydroxyphenol (produced by the cleavage of BPA), a bisphenol A glutathione conjugate, glutathionyl-phenol, glutathionyl 4-isopropylphenol, and BPA dimers. Most of these metabolites apparently share a common metabolic pathway, for which considerable evidence supports the hypothesis of the production of a reactive intermediate, and also helps explain BPA cytotoxicity.

Photo-oxidation of bisphenol A in aqueous solutions at near neutral pH by a Fe(III)-carboxylate complex with oxalacetic acid as a benign molecule

The photo-oxidation of organic pollutants as induced by ferric-carboxylate complexes was known to be a photo-Fenton-like process. The use of a carboxylate ligand with higher efficiency and lower toxicity at near neutral pH is of high interest to researchers. In this work, photo-oxidation of bisphenol A (BPA) induced by a ferric-oxalacetic acid complex in aqueous solutions was investigated under 395 nm LED lamps. The results showed that the rate of BPA degradation increased in the order pH 10.0 8.0 6.5 4.0 within the first 10 min. More than 90% of BPA was successfully oxidized with Fe(III)/oxalacetic acid with a ratio of 1:5 at pH 6.5, which was primarily attributed to the generated hydroxyl radical. Iron in the Fe(III)-oxalacetic acid system was reused by simple addition of oxalacetic acid to the reaction mixture. Compared to common carboxylate ligands (pyruvic acid, oxalic acid, and citric acid), oxalacetic acid is more efficient and environmentally friendly for the Fe(III)-carboxylate complex-based photo-Fenton-like process at near neutral pH.

Preparation of nitrogen doped K2Nb4O11 with high photocatalytic activity for degradation of organic pollutants

Nitrogen doped K2Nb4O11 (K 2Nb4O11-N) has been prepared by solid state reaction between K2Nb4O11 and urea at 400 °C. K2Nb4O11-N has been characterized by XRD, SEM, XPS and UV/vis diffuse reflectance. The photodegradation of various organic pollutants in water by this material, including Orange G (OG), bisphenol A (BPA) and pentachlorophenol (PCP) have been studied at λ > 330 nm and >399 nm. The results show that the photocatalytic activity of K 2Nb4O11-N at >399 nm is higher than those of K2Nb4O11 and Degussa TiO2 P25, indicating the activating effect of nitrogen doping. A mechanism for the photodegradation of organic substrates by K2Nb4O 11-N is proposed.