79414-82-7

Basic information

• Product Name: 1-AMINO-PIPERIDIN-4-OL
• Synonyms: 1-AMINO-PIPERIDIN-4-OL;1-aMino-4-Piperidinol
• CAS NO: 79414-82-7
• Molecular Formula: C₅H₁₂N₂O
• Molecular Weight: 116.16
• Mol File: 79414-82-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-AMINO-PIPERIDIN-4-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-PIPERIDIN-4-OL(79414-82-7)
• EPA Substance Registry System: 1-AMINO-PIPERIDIN-4-OL(79414-82-7)

Safety Data

• Hazardous Substances Data: 79414-82-7(Hazardous Substances Data)

Usage

General Description

1-AMINO-PIPERIDIN-4-OL, also known as AP4 or 4-Aminopiperidin-4-ol, is a chemical compound with the molecular formula C5H12N2O. It is an amino alcohol with a piperidine backbone and a hydroxyl group attached to the fourth carbon. The compound is used in the synthesis of pharmaceutical drugs and as a building block in organic chemistry. It has also been studied for its potential use in the treatment of various medical conditions, including neurological disorders. 1-AMINO-PIPERIDIN-4-OL is considered to be a valuable intermediate in the production of a wide variety of biologically active compounds and is used in both research and industrial applications.

Upstream product

• 55556-93-9 4-hydroxy-N-nitrosopiperidine 
• 5382-16-1 4-HYDROXYPIPERIDINE 

Downstream Products

• 956320-30-2 (R)-3-(4-benzyloxy-2,6-dichloro-benzyl)-1-(4-hydroxy-piperidin-1-yl)-pyrrolidin-2-one 
• 921590-91-2 5-(4-benzyloxyphenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid (4-hydroxypiperidin-1-yl)amide 
• 1427064-47-8 5-(4-cyanophenyl)-N-(4-hydroxypiperidin-1-yl)-6-(2,2,2-trifluoroethoxy)nicotinamide 
• 956320-16-4 (R)-3-(2,6-dichloro-4-hydroxy-benzyl)-1-(4-hydroxy-piperidin-1-yl)-pyrrolidin-2-one 
• 956320-20-0 (R)-4-{3,5-dichloro-4-[1-(4-hydroxy-piperidin-1-yl)-2-oxo-pyrrolidin-3-ylmethyl]-phenoxy }-benzonitrile 
• 956320-38-0 (R)-3-(2-chloro-4-hydroxy-benzyl)-1-(4-triisopropylsilanyloxy-piperidin-1-yl)-pyrrolidin-2-one 
• 956320-15-3 (R)-trifluoro-methanesulfonic acid 3,5-dichloro-4-[1-(4-hydroxy-piperidin-1-yl)-2-oxo-pyrrolidin-3-ylmethyl]-phenyl ester 
• 956320-31-3 (R)-3-(2,6-dichloro-4-hydroxy-benzyl)-1-(4-triisopropylsilanyloxy-piperidin-1-yl)-pyrrolidin-2-one 
• 956320-29-9 (R)-3-(4-benzyloxy-2,6-dichloro-benzyl)-1-(4-triisopropylsilanyloxy-piperidin-1-yl)-pyrrolidin-2-one 
• 956320-39-1 trifluoro-methanesulfonic acid 3-chloro-4-[(R)-2-oxo-1-(4-triisopropylsilanyloxy-piperidin-1-yl)-pyrrolidin-3-ylmethyl]-phenyl ester 

Relevant articles and documents

INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

The present invention discloses novel compounds of Formula I: (I) having 11 -HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11 -HSD type 1 activity.

3-substituted cephem compounds

The present invention relates to novel cephalosporins of the formula (I); STR1 wherein, R1 represents a C1 ?C4 alkyl group or STR2 wherein, R2 and R3, independently, represent hydrogen or a C1 ?C3 alkyl group and R4 represents hydrogen or a C1 ?C4 alkyl group; R1a represents hydrogen or an amino-protecting group; Q represents CH or N; and the formula STR3 represents a saturated or unsaturated heterocyclic group which contains 1 to 4 nitrogen atoms of which one is substituted with an amino group to form quaternary ammonium, and oxygen or sulfur, or a fused heterocyclic group thereof formed together with a substituted or unsubstituted benzene or an optional heterocyclic group, or a pharmaceutically acceptable salt thereof, to processes for preparing the same and to a pharmaceutical composition containing the same as an active ingredient. The compounds(1) according to the invention exhibit potent antibacterial activity and broad antibacterial spectrum against the Gram-positive strains including Staphylococcus as well as Gram-negative strains including Pseudomonas, and, therefore, are expected to be very useful in treatment of various diseases caused by bacterial infection in human beings and animals.