79416-49-2Relevant articles and documents
Palladium Complexes Bearing Chiral bis(NHC) Chelating Ligands on a Spiro Scaffold: Synthesis, Characterization, and Their Application in the Oxidative Kinetic Resolution of Secondary Alcohols
Zhang, Dao,Yu, Jueqin
, p. 605 - 613 (2020/02/13)
A series of chiral bis-N-heterocyclic carbene ligands H2[(S)-1a-d]X2 (X = Br, I) on a spiro scaffold and their palladium complexes (S)-2a-d and (S)-3a,b were prepared and applied in the enantioselective oxidative kinetic resolution of secondary alcohols. The corresponding alcohols can be obtained in high yields with moderate to excellent ee values.
Enantioselective oxidation of racemic secondary alcohols catalyzed by chiral Mn(iii)-salen complexes with N-bromosuccinimide as a powerful oxidant
Xu, Daqian,Wang, Shoufeng,Shen, Zhiqiang,Xia, Chungu,Sun, Wei
supporting information, p. 2730 - 2732 (2012/11/07)
We demonstrate an efficient enantioselective oxidation of secondary alcohols catalyzed by Mn(iii)-salen complex using N-bromosuccinimide (NBS) as the oxidant. The new protocol is very efficient for the oxidative kinetic resolution of a variety of secondary alcohols, including ortho-substituted benzylic alcohols. The Royal Society of Chemistry 2012.
Silylation-based kinetic resolution of monofunctional secondary alcohols
Sheppard, Cody I.,Taylor, Jessica L.,Wiskur, Sheryl L.
supporting information; experimental part, p. 3794 - 3797 (2011/10/02)
The nucleophilic small molecule catalyst (-)-tetramisole was found to catalyze the kinetic resolution of monofunctional secondary alcohols via enantioselective silylation. Optimization of this new methodology allows for selectivity factors up to 25 utilizing commercially available reagents and mild reaction conditions.
