79445-44-6

Basic information

• Product Name: 2-(3,4-DIMETHOXYPHENYL)PYRIDINE
• Synonyms: 2-(3,4-DIMETHOXYPHENYL)PYRIDINE
• CAS NO: 79445-44-6
• Molecular Formula: C₁₃H₁₃NO₂
• Molecular Weight: 215.25
• Mol File: 79445-44-6.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,4-DIMETHOXYPHENYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DIMETHOXYPHENYL)PYRIDINE(79445-44-6)
• EPA Substance Registry System: 2-(3,4-DIMETHOXYPHENYL)PYRIDINE(79445-44-6)

Safety Data

• Hazardous Substances Data: 79445-44-6(Hazardous Substances Data)

Usage

Chemical composition

Composed of a pyridine ring attached to two 3,4-dimethoxyphenyl groups.

Usage

Commonly used as a ligand in coordination chemistry and catalysis, particularly in organometallic and inorganic chemistry.

Potential applications

Development of new organic materials, such as light-emitting diodes and organic photovoltaics.

Biological and medicinal properties

Shown potential as an antioxidant, anti-inflammatory agent, and anticancer activity.

Importance

Has diverse and important applications in various areas of chemistry and potential for further development in both chemical and biological sciences.

Upstream product

• 110-86-1 pyridine 
• 6315-89-5 3,4-dimethoxyaniline 
• 5029-67-4 2-iodopyridine 
• 91-16-7 1,2-dimethoxybenzene 
• 5460-32-2 1-iodo-3,4-dimethoxybenzene 
• 85311-89-3 2-pyridylcopper 
• 27012-25-5 5-bromo-2-phenylpyridine 
• 109-09-1 2-chloropyridine 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 109-04-6 2-bromo-pyridine 
• 895154-77-5 tris(3,4-dimethoxyphenyl)bismuthane 
• 109-76-2 Trimethylenediamine 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 2859-78-1 4-Bromoveratrole 

Downstream Products

• 875656-39-6 2-(3,4-dimethoxyphenyl)-piperidine hydrochloride 
• 1584705-73-6 2-(4,5-dimethoxy-2-(trifluoromethylthio)phenyl)pyridine 

Relevant articles and documents

Chromium-Catalyzed Reductive Cleavage of Unactivated Aromatic and Benzylic C-O Bonds

Reductive cleavage of aromatic and benzylic C-O bonds by chromium catalysis is reported. This deoxygenative reaction was promoted by low-cost CrCl 2precatalyst combined with poly(methyl hydrogen siloxane) as the mild reducing agent, providing a strategy in forming reduced motifs by cleavage of unactivated C-O bonds. A range of functional groups such as bromide, chloride, fluoride, hydroxyl, amino, and alkoxycarbonyl can be retained in the reduction.

Directed Aromatic C-H Activation/Acetoxylation Catalyzed by Pd Nanoparticles Supported on Graphene Oxide

The first solid-supported directed aromatic C-H activation/acetoxylation has been successfully developed by using palladium nanoparticles supported on graphene oxide (PdNPs/GO) as a catalyst. The practicability of this method is demonstrated by simple preparation of catalyst, high catalytic efficiency, wide functional group tolerance, and easy scale up of the reaction. A hot filtration test and Hg(0) poisoning test indicate the heterogeneous nature of the catalytic active species.

Metal-free oxidative cyclization of acetophenones with diamines: A facile access to phenylpyridines

An efficient metal-free access to 2- and 3-phenylpyridines via oxidative coupling of acetophenones or phenylacetones with 1,3-diaminopropane has been described. The reaction involves shorter reaction time, excellent yields and a broad substrate scope. The reaction proceeds via the formation of imine, which further undergoes oxidative C-N bond cleavage, C-C bond formation and oxidation to give a pyridine skeleton. The quantum chemical calculations identified the transition state for the reaction and helped in tracing the reaction mechanism.