794451-94-8 Usage
General Description
1H-Pyrazolo[4,3-c]pyridine,4,5,6,7-tetrahydro-1-methyl-3-(trifluoromethyl)-(9CI) is a chemical compound with a complex structure containing a pyrazole and pyridine ring. It is also known as a 3-trifluoromethyl-1-methyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-c]pyridine. 1H-Pyrazolo[4,3-c]pyridine,4,5,6,7-tetrahydro-1-methyl-3-(trifluoromethyl)-(9CI) is a heterocyclic organic compound with a trifluoromethyl group attached to the third carbon and a methyl group attached to the first carbon of the pyrazole ring. It has potential applications in pharmaceutical and agrochemical industries due to its unique structure and chemical properties. Its precise uses and properties may vary depending on the specific context and formulation.
Check Digit Verification of cas no
The CAS Registry Mumber 794451-94-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,4,4,5 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 794451-94:
(8*7)+(7*9)+(6*4)+(5*4)+(4*5)+(3*1)+(2*9)+(1*4)=208
208 % 10 = 8
So 794451-94-8 is a valid CAS Registry Number.
794451-94-8Relevant articles and documents
Dipeptidyl peptidase IV inhibitors derived from β-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole
Ashton, Wallace T.,Sisco, Rosemary M.,Dong, Hong,Lyons, Kathryn A.,He, Huaibing,Doss, George A.,Leiting, Barbara,Patel, Reshma A.,Wu, Joseph K.,Marsilio, Frank,Thornberry, Nancy A.,Weber, Ann E.
, p. 2253 - 2258 (2007/10/03)
A series of β-aminoacylpiperidines bearing various fused five-membered heterocyclic rings was synthesized as dipeptidyl peptidase IV inhibitors. Potent and relatively selective inhibition could be obtained, depending on choice of heterocycle, regioisomerism, and substitution. In particular, one analog (74, DPP-IV IC50 = 26 nM) exhibited good oral bioavailability and acceptable half-life in the rat, albeit with rather high clearance.
