794564-44-6

Basic information

• Product Name: 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-ethyl-2-(β-D-glucopyranosyloxy)-6-hydroxyphenyl]-1-propanone
• Synonyms: 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-ethyl-2-(β-D-glucopyranosyloxy)-6-hydroxyphenyl]-1-propanone
• CAS NO: 794564-44-6
• Molecular Formula: C25H30O10
• Molecular Weight: 490.4997
• Product Categories: Carbohydrates & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 794564-44-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-ethyl-2-(β-D-glucopyranosyloxy)-6-hydroxyphenyl]-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-ethyl-2-(β-D-glucopyranosyloxy)-6-hydroxyphenyl]-1-propanone(794564-44-6)
• EPA Substance Registry System: 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-ethyl-2-(β-D-glucopyranosyloxy)-6-hydroxyphenyl]-1-propanone(794564-44-6)

Safety Data

• Hazardous Substances Data: 794564-44-6(Hazardous Substances Data)

Usage

Uses

3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-ethyl-2-(β-D-glucopyranosyloxy)-6-hydroxyphenyl]-1-propanone is a glycosylated dihydrochalcone and is a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor.

Upstream product

• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 209746-97-4 4'-ethyl-2',6'-dihydroxyacetophenone 2'-O-(2,3,4,6-O-tetraacetyl)-β-D-glucopyranoside 
• 209746-96-3 4'-ethyl-2',6'-dihydroxyacetophenone 
• 4299-72-3 5-ethylresorcinol 

Relevant articles and documents

Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors

A series of glucose conjugates was synthesized and tested for inhibition of SGLT1 and SGLT2.