79478-02-7

Basic information

• Product Name: Benzeneacetic acid, a-oxo-4-(trifluoromethyl)-
• CAS NO: 79478-02-7
• Molecular Formula: C9H5F3O3
• Molecular Weight: 218.132
• Mol File: 79478-02-7.mol
• Article Data: 42

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-oxo-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-oxo-4-(trifluoromethyl)-(79478-02-7)
• EPA Substance Registry System: Benzeneacetic acid, a-oxo-4-(trifluoromethyl)-(79478-02-7)

Safety Data

• Hazardous Substances Data: 79478-02-7(Hazardous Substances Data)

Upstream product

• 402-50-6 1-trifluoromethyl-4-vinyl-benzene 
• 73183-23-0 2-(4-(trifluoromethyl)phenyl)-2-((trimethylsilyl)oxy)acetonitrile 
• 156276-22-1 methyl 2-hydroxy-2-(4-(trifluoromethyl)phenyl)acetate 
• 132115-87-8 (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester 
• 395-35-7 4-(trifluoromethyl)mandelic acid 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 1236046-47-1 (2-(pyridin-2’-yl)phenyl)(4-(trifluoromethyl)phenyl)methanone 
• 120301-10-2 N-(2-(4-(trifluoromethyl)benzoyl)phenyl)acetamide 
• 1613439-78-3 2-(4-trifluoromethylphenyl)-N-(3-(N,N-dimethylaminocarbonylphenyl))-2-oxoacetamide 
• 1463489-20-4 tert-butyl 2-oxo-2-[4-(trifluoromethyl)phenyl]acetate 
• 720702-68-1 ethyl 5?[4?(trifluoromethyl)phenyl]?1,3,4?oxadiazole?2?carboxylate 

Relevant articles and documents

Synthesis of α-Keto Acids via Oxidation of Alkenes Catalyzed by a Bifunctional Iron Nanocomposite

An efficient methodology for synthesis of α-keto acids via oxidation of alkenes using TBHP as oxidant catalyzed by a bifunctional iron nanocomposite has been established. A variety of alkenes with different functional groups were smoothly oxidized into their corresponding α-keto acids in up to 80% yield. Moreover, the bifunctional iron nanocomposite catalyst showed outstanding catalytic stability for successive recycles without appreciable loss of activity.

Self-Assembled 2,3-Dicyanopyrazino Phenanthrene Aggregates as a Visible-Light Photocatalyst

In this study, 2,3-dicyanopyrazino phenanthrene (DCPP), a commodity chemical that can be prepared at an industrial scale, was used as a photocatalyst in lieu of Ru or Ir complexes in C-X (X = C, N, and O) bond-forming reactions under visible-light irradiation. In these reactions, [DCPP]n aggregates were formed in situ through physical π-πstacking of DCPP monomers in organic solvents. These aggregates exhibited excellent photo- and electrochemical properties, including a visible light response (430 nm), long excited-state lifetime (19.3 μs), high excited-state reduction potential (Ered([DCPP]n*/[DCPP]n·-) = +2.10 V vs SCE), and good reduction stability. The applications of [DCPP]n aggregates as a versatile visible-light photocatalyst were demonstrated in decarboxylative C-C cross-coupling, amidation, and esterification reactions.

Photoinduced homolytic decarboxylative acylation/cyclization of unactivated alkenes with α-keto acid under external oxidant and photocatalyst free conditions: access to quinazolinone derivatives

A novel and green strategy for the synthesis of acylated quinazolinone derivativesviaphoto-induced decarboxylative cascade radical acylation/cyclization of quinazolinone bearing unactivated alkenes has been developed. The protocol provides a novel route to access acyl radicals from α-keto acids through a self-catalyzed energy transfer process. Most importantly, the reaction proceeded smoothly without any external photocatalyst, additive or oxidant, and could be easily scaled-up in flow conditions with sunlight irradiation.