79493-89-3Relevant articles and documents
Studies on Biologically Active Pteridines. VII. Absolute Configuration of (-)-6-Methyltetrahydropterin Produced by Enzymic Reduction
Matsuura, Sadao,Sugimoto, Takashi
, p. 2543 - 2544 (1981)
The C-6 configuration of (-)-6-methyltetrahydropterin, produced by enzymic reduction of the 7,8-dihydro precursor, is shown to be S by a synthesis.Condensation of 2,4-diamino-5-bromo-6-hydroxypyrimidine with (S)-1,2-propanediamine gave (S)-6-methyltetrahydropterin.Examination of CD spectra of the 6-methyltetrahydropterins from the two origins led to the above conclusion.