79499-53-9

Basic information

• Product Name: 2,2-Dibromo-6-(2-chlorophenyl)-6-(methylamino)cyclohexanone
• Synonyms: 2,2-Dibromo-6-(2-chlorophenyl)-6-(methylamino)cyclohexanone
• CAS NO: 79499-53-9
• Molecular Weight: 395.521
• Mol File: 79499-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-Dibromo-6-(2-chlorophenyl)-6-(methylamino)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dibromo-6-(2-chlorophenyl)-6-(methylamino)cyclohexanone(79499-53-9)
• EPA Substance Registry System: 2,2-Dibromo-6-(2-chlorophenyl)-6-(methylamino)cyclohexanone(79499-53-9)

Safety Data

• Hazardous Substances Data: 79499-53-9(Hazardous Substances Data)

Upstream product

• 6740-88-1 ketamine 

Relevant articles and documents

Synthesis of Ketamine Metabolites I and II and Some Anomalous Reactions of 6-Bromoketamine

Two metabolites of the drug ketamine, 2-(2-chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride (1), have been synthesized.They are the N-demethyl compound, metabolite I (13), and the N-demethyl-5,6-dehydro analogue, metabolite II (15).Three bromo ketone derived from ketamine have also been synthesized and their realtive configuration assigned.In addition, attempted dehydrohalogenation of axial 2-bromoketamine (2a) with sodium amide in liquid ammonia has produced a novel entry into the 6-azabicycloheptane ring system.The structure of the rearrangement product (3) has been confirmed by unequivocal synthesis.Other unusual reactions include the reduction of an N-alkylazetidinone to an N-alkylazetidine and an acid-catalyzed N-alkyl cleavage of a β-lactam.