79510-57-9Relevant articles and documents
Synthesis of novel isoxazolyl bis-thiazolo[3,2-a]pyrimidines
Rajanarendar,Ramakrishna,Rama Murthy
scheme or table, p. 899 - 902 (2012/09/07)
A new synthetic strategy for the synthesis of novel 3-(3-(3-methyl-4- nitroisoxazol-5-yl)-2-phenyl-1-(5,7-diaryl-7H-thiazolo[3,2-a]pyrimidin-3-yl) propyl)-5,7-diaryl-7H-thiazolo[3,2-a] pyrimidines (7a-i) analogues is described. Reaction of 3-(2-(3-methyl-4-nitroisoxazole-5-yl)-1-phenylethyl)pentane-2,4- dione (3) with two moles of thiourea in presence of iodine and CuO afforded 4-(1-(2-aminothiazol-4-yl)-3-(3-methyl-4-nitroisoxazol-5-yl)-2-aryl propyl-thiazol-2-amine (5). Compound 5 on reaction with two moles of chalcone (6) furnished novel 3-(3-(3-methyl-4-nitroisoxazol-5-yl)-2-phenyl-1-(5,7-diaryl- 7H-thiazolo[3,2-a]pyrimidin-3-yl)propyl)-5,7-diaryl-7H-thiazolo[3,2-a] pyrimidines (7a-i).
Multi-component synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N- oxides
Rajanarendar,Nagi Reddy,Rama Murthy
, p. 927 - 930 (2011/11/12)
A three component one-pot protocol was investigated for the synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N-oxides from commercially available materials.
Multicomponent synthesis of spiroisoxazolines
Adamo, Mauro F. A.,Donati, Donato,Duffy, Eleanor F.,Sarti-Fantoni, Piero
, p. 8395 - 8399 (2007/10/03)
A three-component one-pot procedure (3-MCR) was developed to assemble the spiroisoxazoline nucleus from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography.