796071-90-4

Basic information

• Product Name: (5-FLUOROINDOL-1-YL)ACETIC ACID
• Synonyms: (5-FLUOROINDOL-1-YL)ACETIC ACID;2-(5-Fluoro-1H-indol-1-yl)acetic acid
• CAS NO: 796071-90-4
• Molecular Formula: C10H8FNO2
• Molecular Weight: 193.17
• EINECS: 604-604-1
• Mol File: 796071-90-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 388.5 °C at 760 mmHg
• Flash Point: 188.7 °C
• Appearance: /
• Density: 1.33 g/cm³
• Vapor Pressure: 9.91E-07mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (5-FLUOROINDOL-1-YL)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (5-FLUOROINDOL-1-YL)ACETIC ACID(796071-90-4)
• EPA Substance Registry System: (5-FLUOROINDOL-1-YL)ACETIC ACID(796071-90-4)

Safety Data

• Hazardous Substances Data: 796071-90-4(Hazardous Substances Data)

Usage

General Description

(5-Fluoroindol-1-yl)acetic acid is a chemical compound that belongs to the class of indole derivatives. It is a derivative of indole with a fluorine atom attached to the 5-position and an acetic acid group attached to the nitrogen atom. (5-FLUOROINDOL-1-YL)ACETIC ACID has potential applications in medicinal chemistry and pharmaceutical research due to its ability to modify biological systems via interactions with receptors and enzymes. It may also have potential use as a building block in the synthesis of other more complex organic molecules. Further research is needed to fully understand the potential uses and properties of (5-fluoroindol-1-yl)acetic acid.

InChI:InChI=1/C10H8FNO2/c11-8-1-2-9-7(5-8)3-4-12(9)6-10(13)14/h1-5H,6H2,(H,13,14)

Upstream product

• 399-52-0 5-fluoro-1H-indole 
• 1343059-96-0 C₁₁H₁₀FNO₂ 
• 1340128-44-0 ethyl 2-(5-fluoro-1H-indol-1-yl)acetate 
• 1344079-83-9 2-(5-fluoro-1H-indol-1-yl)acetonitrile 

Relevant articles and documents

CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN-RELATED PEPTIDASE 6 (KLK6)

The invention relates to compounds which are suitable for the treatment of a disease associated with kallikrein-like peptidase 6 overexpression and to pharmaceutical compositions containing such compounds. The invention further relates to a kit of parts comprising such compounds or pharmaceutical compositions.

Indolyl and dihydroindolyl N-glycinamides as potent and in vivo active NPY5 antagonists

A novel series of indolyl and dihydroindolyl glycinamides were identified as potent NPY5 antagonists with in vivo activity from screen hit 1. The dihydroindolyl glycinamide 10a significantly inhibits NPY5 agonist induced feeding at a dose of 0.1 mg/kg. The indolyl glycinamide 12c also inhibits NPY5 agonist induced feeding at a dose of 1 mg/kg. Both compounds 10a and 12c represent potential tools for further investigation into the biology of the NPY5 receptor.

SUBSTITUTED AMINO CARBOXYLIC ACIDS

Disclosed are compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of the invention include inhibitors of Protein tyrosine phosphatases, in particular Protein tyrosine phosphatase-1B (PTP-1B), that are useful in the treatment of diabetes and other PTP mediated diseases, such as cancer, neurodegenerative diseases and the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.