796090-24-9 Usage
General Description
6-Chloro-3-(trifluoromethyl)pyridine-2-carboxylic acid is a chemical compound with the molecular formula C7H3ClF3NO2. It is a pyridine derivative with a carboxylic acid group and a chlorine atom at the 6th carbon position, as well as a trifluoromethyl group at the 3rd carbon position. 6-Chloro-3-(trifluoromethyl)pyridine-2-carboxylic acid is commonly used in the pharmaceutical industry as a building block for the synthesis of various drug molecules and active pharmaceutical ingredients (APIs). It has potential applications in the development of drugs for the treatment of various diseases and medical conditions. Additionally, it can also be used as a reagent in organic synthesis and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 796090-24-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,6,0,9 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 796090-24:
(8*7)+(7*9)+(6*6)+(5*0)+(4*9)+(3*0)+(2*2)+(1*4)=199
199 % 10 = 9
So 796090-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H3ClF3NO2/c8-4-2-1-3(7(9,10)11)5(12-4)6(13)14/h1-2H,(H,13,14)
796090-24-9Relevant articles and documents
Three chloro(trifluoromethyl)pyridines as model substrates for regioexhaustive functionalization
Cottet, Fabrice,Schlosser, Manfred
, p. 3793 - 3798 (2007/10/03)
As a further test of the concept of regioexhaustive functionalization, 2-chloro-6-(trifluoromethyl)pyridine, 2-chloro-5-(trifluoromethyl)pyridine and 3-chloro-4-(trifluoromethyl)-pyridine were each converted into the three possible carboxylic acids 2, 4, 6, 8, 10, 12, 16, 17 and 20. This was achieved by employing several, but not all of the organometallic "tool-box methods": transformation of a more basic organometallic species into a less basic isomer by transmetalation-equilibration, site discriminating deprotonation with lithium N,N-diisopropylamide or lithium 2,2,6,6- tetramethylpiperidide, regio-divergent iodine migration and steric screening of acidic positions by a bulky trialkylsilyl group. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
