79612-79-6

Basic information

• Product Name: Propanoic acid, 3-[(4-bromophenyl)amino]-3-oxo-, ethyl ester
• CAS NO: 79612-79-6
• Molecular Formula: C11H12BrNO3
• Molecular Weight: 286.125
• Mol File: 79612-79-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3-[(4-bromophenyl)amino]-3-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3-[(4-bromophenyl)amino]-3-oxo-, ethyl ester(79612-79-6)
• EPA Substance Registry System: Propanoic acid, 3-[(4-bromophenyl)amino]-3-oxo-, ethyl ester(79612-79-6)

Safety Data

• Hazardous Substances Data: 79612-79-6(Hazardous Substances Data)

Upstream product

• 36239-09-5 ethyl chlorocarbonylacetate 
• 106-40-1 4-bromo-aniline 
• 105-53-3 diethyl malonate 

Downstream Products

• 1266620-09-0 C₁₈H₂₆BrN₃O₂ 
• 54675-23-9 6-bromo-4-hydroxyquinoline-2(1H)-one 
• 79613-04-0 2-Ethoxycarbonyl-3-anilino-3-methylthio-acrylsaeure-p-bromanilid 
• 79612-87-6 2-(4-Bromo-phenylcarbamoyl)-3,3-bis-ethylsulfanyl-acrylic acid ethyl ester 
• 79612-96-7 N-(4-Bromo-phenyl)-2-[1,3]dithian-2-ylidene-malonamic acid ethyl ester 
• 79612-89-8 N-(4-Bromo-phenyl)-2-[1,3]dithiolan-2-ylidene-malonamic acid ethyl ester 
• 79612-80-9 2-(4-Bromo-phenylcarbamoyl)-3,3-bis-methylsulfanyl-acrylic acid ethyl ester 
• 79612-99-0 2-Ethoxycarbonyl-2-(4-bromphenyl-carbamoyl)-dithioessigsaeuremethylester 
• 95262-09-2 3-[(4-bromophenyl)amino]-3-oxopropanoic acid 
• 103-88-8 4-bromoacetanilide 

Relevant articles and documents

SYNTHESIS AND PROPERTIES OF AMIDES OF 2-SUBSTITUTED 3-ARYL- AND 3-PYRIDYLAMINOACRYLIC ACIDS

The reaction of aryl- or pyridylamines with ethyl orthoformate and malonanilic acid gave amides of 2-(N-arylcarbamoyl)-, 2-cyano-, 2-ethoxycarbonyl-3-aryloaminoacrylic acids and their corresponding 3-pyridyl analogs.IR and PMR spectroscopy indicates that

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The present invention provides compounds of Formula (I), or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, R3 and R11 are as defined herein. The compounds of Formula (I) are useful as selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.