79617-15-5

Basic information

• Product Name: [10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-3,4,9-trihydroxy-12-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-14-oxo-oxacyclotetradec-6-yl]-carbamic acid benzyl ester
• Synonyms: [10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-3,4,9-trihydroxy-12-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-14-oxo-oxacyclotetradec-6-yl]-carbamic acid benzyl ester
• CAS NO: 79617-15-5
• Molecular Weight: 869.103
• Mol File: 79617-15-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-3,4,9-trihydroxy-12-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-14-oxo-oxacyclotetradec-6-yl]-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-3,4,9-trihydroxy-12-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-14-oxo-oxacyclotetradec-6-yl]-carbamic acid benzyl ester(79617-15-5)
• EPA Substance Registry System: [10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-ethyl-3,4,9-trihydroxy-12-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-14-oxo-oxacyclotetradec-6-yl]-carbamic acid benzyl ester(79617-15-5)

Safety Data

• Hazardous Substances Data: 79617-15-5(Hazardous Substances Data)

Upstream product

• 114-07-8 erythromycin 
• 13127-18-9 (9-E)-deoxo-9-hydroximinoerythromycin A 
• 26116-56-3 erythromycylamine 
• 501-53-1 benzyl chloroformate 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 

Downstream Products

• 497832-40-3 C₅₇H₁₀₄N₂O₁₄Si₂ 
• 497832-43-6 C₄₉H₇₇N₅O₁₄ 
• 497832-45-8 C₅₉H₉₅N₅O₁₅ 
• 497832-06-1 C₄₉H₈₇N₅O₁₂ 
• 497832-41-4 C₆₀H₁₁₁N₃O₁₄Si₂ 
• 497832-02-7 C₄₃H₇₃N₃O₁₂ 
• 497832-42-5 C₄₅H₇₅N₃O₁₃ 
• 850220-44-9 C₅₀H₈₄N₄O₁₆ 
• 79541-37-0 acetic acid 2-[10-benzyloxycarbonylamino-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-2-oxo-oxacyclotetradec-6-yloxy]-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester 

Relevant articles and documents

Synthetic method of isotope-labeled erythromycylamine

The invention discloses a synthetic method of isotope-labeled erythromycylamine, belongs to the field of drug metabolism, and provides a synthetic method which is reasonable in process design, strongin operability and high in yield, can efficiently convert isotope-labeled raw materials into labeled target products, and can realize industrial production of isotope-labeled erythromycylamine. The method takes 13CD3 labeled methyl iodide as a starting raw material, the isotope-labeled erythromycylamine is synthesized by six steps of reactions, optimal preparation steps and reaction conditions arescreened out through a large number of experiments, the whole process is reasonable in design and high in operability, the labeled raw materials can be efficiently converted into labeled target products, the chemical purity of the labeled erythromycylamine prepared through the method can reach 98.5% or above, and the labeled isotope abundance is larger than 98.5%.

Design, synthesis, and biological evaluation of BODIPY-erythromycin probes for bacterial ribosomes

BODIPY-erythromycin probes of bacterial ribosomes were designed and synthesized by attaching a BODIPY fluorophore to the 4″- and 9-positions of the erythromycin structure. The probes exhibited excellent binding affinity to bacterial