796702-45-9Relevant articles and documents
MOLECULES AND METHODS RELATED TO TREATMENT OF UNCONTROLLED CELLULAR PROLIFERATION
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Paragraph 00437, (2021/02/05)
The present disclosure relates to chemical compounds that modulate cellular proliferation for the treatment of uncontrolled cellular proliferation disorders (such as cancer), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening
Khersonsky, Sonya M.,Jung, Da-Woon,Kang, Tae-Wook,Walsh, Daniel P.,Moon, Ho-Sang,Jo, Hakryul,Jacobson, Eric M.,Shetty, Vivekananda,Neubert, Thomas A.,Chang, Young-Tae
, p. 11804 - 11805 (2007/10/03)
An improved forward chemical genetics approach was successfully demonstrated using a tagged library concept. A small-molecule triazine library with linkers was used to screen for brain/eye developmental phenotypes in a zebrafish embryo system. This approa