796847-67-1Relevant articles and documents
Discovery and pharmacological profile of new 1H-indazole-3-carboxamide and 2H-pyrrolo[3,4-c]quinoline derivatives as selective serotonin 4 receptor ligands
Furlotti, Guido,Alisi, Maria Alessandra,Apicella, Claudia,Capezzone De Joannon, Alessandra,Cazzolla, Nicola,Costi, Roberta,Cuzzucoli Crucitti, Giuliana,Garrone, Beatrice,Iacovo, Alberto,Magarò, Gabriele,Mangano, Giorgina,Miele, Gaetano,Ombrato, Rosella,Pescatori, Luca,Polenzani, Lorenzo,Rosi, Federica,Vitiello, Marco,Di Santo, Roberto
, p. 9446 - 9466 (2013/01/16)
Since the discovery of the serotonin 4 receptor (5-HT4R), a large number of receptor ligands have been studied. The safety concerns and the lack of market success of these ligands have mainly been attributed to their lack of selectivity. In thi