79822-58-5Relevant articles and documents
Palladium-catalyzed novel arylations of cyclic β-bromo α,β-unsaturated aldehydes with triarylbismuths as multicoupling organometallic nucleo-philes
Rao, Maddali L. N.,Banerjee, Debasis,Dhanorkar, Ritesh J.
supporting information; experimental part, p. 273 - 279 (2011/04/16)
Cross-coupling arylations of cyclic β-bromo α,β -unsaturated aldehydes were carried out with triarylbismuths as atom-efficient multicoupling organometallic reagents under palladium-catalyzed conditions. These reactions afforded the corresponding arylated alkenes in an efficient manner with good to high yields. Georg Thieme Verlag Stuttgart.
Pyridine compounds which are useful in treating a disease state characterized by an excess of platelet activating factors
-
, (2008/06/13)
The invention relates to compounds of the formula STR1 wherein Y and Y' are hydrogen or taken together are O or S, *A is paraphenylene or *----(CH2)n --(X)s --(CH2)r ----, X is O, S or --CH=CH--, n or r, independently, are integers from 0 to 3, m is an integer from 0 to 1, s is an integer from 0 to 1, provided that when s is 1, n+m must be at least 2, t is an integer from 0 to 10, R1 and R2, independently, are lower alkyl, lower alkenyl or aryl, or one of R1 or R2 is hydrogen and the other is STR2 wherein W is STR3 --CH2 --CH2 --, --CH2 --, O, S, or STR4 and X1 is lower alkyl, phenyl unsubstituted or mono-, di- or trisubstituted by lower alkoxy, lower alkyl or halogen, and X2, X3 and X4, independently, are hydrogen, lower alkyl, lower alkoxy or halogen, R3 is hydrogen, lower alkyl or aryl, R4 is hydrogen, lower alkyl, aryl, aryl-lower alkyl or acyl, R5 is hydrogen or lower alkyl, R6 is hydrogen, lower alkyl, cycloalkyl, Het-lower alkyl or aryl, Het is a monocyclic 6-membered heteroaromatic radical containing one or two nitrogen atoms, which radical may be substituted by lower alkyl, halogen or aryl, and the asterisk denotes the point of attachment, and when R5 and R6 are different, their enantiomers and racemic mixtures thereof, when R1 and R2 are different, their geometric isomers, and pharmaceutically acceptable acid addition salts thereof.
Applications of the Vilsmeier Reaction. 13. Vilsmeier Approach to Polycyclic Aromatic Hydrocarbons
Reddy, M. Parameswara,Rao, G. S. Krishna
, p. 5371 - 5373 (2007/10/02)
The synthesis of three typical polycyclic hydrocarbons (PAH) has been described, wherein the Vilsmeier reaction plays a major role.Vilsmeier reaction of the tetralol 1 gives the dihydronaphthaldehyde 2 which on cyclodehydration gives the dihydroarene 3.It
