798563-50-5

Basic information

• Product Name: 2-(2-fluoro-5-Methoxyphenyl)acetic acid
• Synonyms: 2-(2-fluoro-5-Methoxyphenyl)acetic acid;(2-Fluoro-5-methoxyphenyl)acetic acid, 3-(Carboxymethyl)-4-fluoroanisole;2-Fluoro-5-methoxyphenylacetic acid 97%;2-Fluoro-5-methoxyphenylaceticacid97%
• CAS NO: 798563-50-5
• Molecular Formula: C₉H₉FO₃
• Molecular Weight: 184.1643632
• Mol File: 798563-50-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 317.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.269±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.91±0.10(Predicted)
• CAS DataBase Reference: 2-(2-fluoro-5-Methoxyphenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-fluoro-5-Methoxyphenyl)acetic acid(798563-50-5)
• EPA Substance Registry System: 2-(2-fluoro-5-Methoxyphenyl)acetic acid(798563-50-5)

Safety Data

• Hazardous Substances Data: 798563-50-5(Hazardous Substances Data)

Usage

General Description

2-(2-fluoro-5-methoxyphenyl)acetic acid is a chemical compound consisting of a benzene ring with a fluorine atom and a methoxy group attached to it, and a carboxylic acid group. It is used as a building block in organic synthesis and pharmaceutical research, with potential applications in the development of new drugs. 2-(2-fluoro-5-Methoxyphenyl)acetic acid has shown promising pharmacological activities, including anti-inflammatory and analgesic properties, which make it a potential candidate for the development of novel medications. Its unique structure and properties also make it a valuable tool for studying the structure-activity relationships of various compounds in medicinal chemistry.

Upstream product

• 672931-28-1 2-(2-fluoro-5-methoxyphenyl)acetonitrile 
• 2338-54-7 4-fluoro-3-methylanisol 
• 143-33-9 sodium cyanide 
• 1418126-43-8 2,2,2-trichloro-1-(2-fluoro-5-methoxyphenyl)ethanol 
• 105728-90-3 2-fluoro-5-methoxybenzaldehyde 

Downstream Products

• 1344688-70-5 C₂₂H₂₆FNO₆ 
• 149029-89-0 2-(2-fluoro-5-hydroxyphenyl)acetic acid 
• 459215-67-9 2-(5-(benzyloxy)-2-fluorophenyl)acetic acid 
• 1418126-44-9 2-(5-(benzyloxy)-2-fluorophenyl)acetyl chloride 
• 1418126-21-2 3-((6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-4-fluorophenol 
• 1418126-45-0 2-(5-(benzyloxy)-2-fluorophenyl)-N-(3,4-dimethoxyphenethyl)-N-methylacetamide 
• 1418126-47-2 1-(5-(benzyloxy)-2-fluorobenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 798563-56-1 4-chloromethyl-1-(2-fluoro-5-methoxy-benzyl)-6,7-dimethoxy-isoquinoline 
• 798563-55-0 1-(2-fluoro-5-methoxybenzyl)-4-hydroxymethyl-6,7-dimethoxyisoquinoline 
• 798563-57-2 C₂₀H₁₉FN₄O₃ 
• 798563-51-6 1-(2-fluoro-5-methoxybenzyl)-4-ethoxycarbonyl-6,7-dimethoxyisoquinoline 
• 1344688-82-9 C₂₂H₂₄FNO₅ 

Relevant articles and documents

COMPOUNDS AND THEIR METHODS OF USE

Compounds and compositions comprising compounds that inhibit glutaminase are described herein. Also described herein are methods of using the compounds that inhibit glutaminase in the treatment of cancer.

COMPOUNDS AND THEIR METHODS OF USE

Provided are compounds of formula (I), which can inhibit glutaminase. Pharmaceutical compositions comprising these compounds and uses as glutaminase inhibitors for treating cancers thereof are also provided.

FURAN OR THIOPHENE DERIVATIVE AND MEDICINAL USE THEREOF

The present invention provides a compound represented by the formula (I): [wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, p is 0, 1 or 2, and when p is 2, each R may be the same or different, R1 is a hydrogen atom or an optionally substituted hydrocarbon group, R2 is an optionally substituted aromatic group, Ring A is an optionally substituted monocyclic aromatic ring or optionally substituted bicyclic aromatic fused ring, X1 is an oxygen atom or a sulfur atom, X2 is a bond, an oxygen atom or -S(O)n- (wherein n is 0, 1 or 2), Y is a bond, an oxygen atom, -S(O)m-, -C(=O)-N(R3)- or -N(R3)-C(=O)- (R3 is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, and m is 0, 1 or 2), M1, M2 and M3 may be the same or different and are each independently a bond or an optionally substituted divalent aliphatic hydrocarbon group, and M4 is an optionally substituted divalent aliphatic hydrocarbon group] or a salt thereof, which is useful as a prophylactic and/or therapeutic agent for lipid metabolism abnormality, arteriosclerotic disease and sequelae thereof, diabetes mellitus and the like.