79888-13-4

Basic information

• Product Name: methyl 2,3,5,6,11,11b-hexahydro-3-oxo-1H-indolizino<8,7-b>indole-11b-carboxylate
• CAS NO: 79888-13-4
• Molecular Weight: 284.315
• Mol File: 79888-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,3,5,6,11,11b-hexahydro-3-oxo-1H-indolizino<8,7-b>indole-11b-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,5,6,11,11b-hexahydro-3-oxo-1H-indolizino<8,7-b>indole-11b-carboxylate(79888-13-4)
• EPA Substance Registry System: methyl 2,3,5,6,11,11b-hexahydro-3-oxo-1H-indolizino<8,7-b>indole-11b-carboxylate(79888-13-4)

Safety Data

• Hazardous Substances Data: 79888-13-4(Hazardous Substances Data)

Upstream product

• 13192-04-6 dimethyl 2-ketoglutarate 
• 343-94-2 tryptamine hydochloride 

Downstream Products

• 60755-86-4 1-methoxycanthin-6-one 

Relevant articles and documents

Facile synthesis of 2,3,6,11-tetrahydro-1H,5H-indolizino[8,7-b]indole-11b- carboxylic acid methyl ester via a 9-BBN-mediated tertiary lactam reduction

A facile synthesis of 2,3,6,11-tetrahydro-1H,5H-indolizino[8,7-b]indole- 11b-carboxylic acid methyl ester, a versatile intermediate utilized in the synthesis of indole alkaloids, was achieved in two steps. Condensation of tryptamine with dimethyl α-ketoglutarate led to the formation of the corresponding indolizino[8,7-b]indolone ester, which subsequently underwent an efficient lactam reduction with 9-BBN to generate the tertiary amine ester in good yield. Copyright Taylor & Francis Group, LLC.