79889-93-3Relevant articles and documents
Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors
Christodoulou, Michael S.,Colombo, Francesco,Passarella, Daniele,Ieronimo, Gabriella,Zuco, Valentina,De Cesare, Michelandrea,Zunino, Franco
, p. 1649 - 1657 (2011/04/21)
Since activation of p53 in response to cytotoxic stress may have proapoptotic or protective effects depending on the nature of the injury, inhibitors of p53 may have therapeutic interest as modulators of chemotherapy toxicity or efficacy. In an attempt to
2-Phenylimidazo [2,1-b]benzothiazole derivatives
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, (2008/06/13)
A novel 2-phenylimidazo[2,1-b]benzothiazole derivative shown by the following formula STR1 or a salt thereof which possesses an immunoregulatory action and is useful as an antiallergic agent, an antiasthmatic, and a suppressant of rejection at tissue tran